An opioid peptide from synganglia of the tick, Amblyomma testindinarium
文献类型：期刊论文
| 作者 | Liang JG1; Zhang J2,3; Lai R[*]1,2; Rees HH4 |
| 刊名 | PEPTIDES
 |
| 出版日期 | 2005 |
| 卷号 | 26期号:4页码:603-606 |
| 关键词 | ticks synganglia opioid peptides defensive reaction |
| ISSN号 | 0196-9781 |
| 通讯作者 | rlai72@njau.edu.cn |
| 合作状况 | 其它 |
| 英文摘要 | An opioid peptide, which shares similarity with mammalian hemorphins, has been identified from the synganglia (central nervous system) of the hard tick, Amblyomma testindiarium. Its primary sequence was established as LVVYPWTKM that contains a tetrapeptide sequence Tyr-Pro-Trp-Thr of hemorphin-like opioid peptides. By hot-plate bioassay, the purified peptide and synthetic peptide displayed dose-related antinociceptive effect in mice, as observed for other hemorphin-like opioid peptides. This is the first opioid peptide identified from ticks. Ticks may utilize the opioid peptide in their strategy to escape host immuno-surveillance as well as in inhibiting responses directed against themselves. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by Chinese National Natural Science Foundation (30200044/C01040101). |
| 原文出处 | 200526603.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2475]  |
| 专题 | 昆明动物研究所_动物毒素室 |
| 作者单位 | 1.School of Biological Sciences, Nanjing Agriculture University, Nanjing, Jiangshu 210095, China 2.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China 3.Graduate School of the Chinese Academy of Sciences, Beijing 100009, China 4.School of Biological Sciences, University of Liverpool, The Biosciences Building, Crown Street, Liverpool L69 7ZB, UK |
| 推荐引用方式 GB/T 7714 | Liang JG,Zhang J,Lai R[*],et al. An opioid peptide from synganglia of the tick, Amblyomma testindinarium[J]. PEPTIDES,2005,26(4):603-606. |
| APA | Liang JG,Zhang J,Lai R[*],&Rees HH.(2005).An opioid peptide from synganglia of the tick, Amblyomma testindinarium.PEPTIDES,26(4),603-606. |
| MLA | Liang JG,et al."An opioid peptide from synganglia of the tick, Amblyomma testindinarium".PEPTIDES 26.4(2005):603-606. |
入库方式： OAI收割
来源：昆明动物研究所
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