The mastoparanogen from wasp
文献类型：期刊论文
| 作者 | Xu XQ1,3; Yang HL1,4; Yu HN2; Li JX1,3; Lai R[*]1 |
| 刊名 | PEPTIDES
 |
| 出版日期 | 2006 |
| 卷号 | 27期号:12页码:3053-3057 |
| 关键词 | Wasp venom Vespa magnifica Mastoparan Mastoparanogen Precursor G-protein |
| ISSN号 | 0196-9781 |
| 通讯作者 | rlai@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Mastoparans are a family of small peptides identified from the venom of hymenopteroid insects. Although they have been characterized as early as 1979, and so far are recognized as a leading biomolecule in potential drug therapy, their precursors, mastoparanogen, have still not been determined. In this paper, several mastoparans from the venom of the wasp Vespa magnifica (Smith) are reported. The cDNA of mastoparanogen is 236 base pairs in length, and encodes 40 amino acid residues, including a N-terminal acidic fragment and a C-terminal mature basic mastoparan, which contain multiple acidic amino acid residues and a tetradecapeptide with three lysines, INLKAIAALAKKLLG, respectively. The glycine at the tetradecapeptide end is the donator of -NH(4) for the amidation of the leucine at the C-terminal. As far as we know, this is the first report of the precursor of animal mastoparan. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the Chinese National Natural Science Foundation (30570360), Yunnan Natural Science Foundation (2005C0054M) and Jiangsu Natural Science Foun- dation (BK2005422). |
| 原文出处 | 2006273053.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2481]  |
| 专题 | 昆明动物研究所_动物毒素室 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Biotoxin Units of Key Laboratories of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China 2.College of Life Sciences School of Heibei Normal University, Shijiazhuang, Hebei 050016, China 3.Graduate School of the Chinese Academy of Sciences, Beijing 100009, China 4.College of Animal Sciences and Technology, Jiangxi Agricultural University, Nanchang 330045, Jiangxi, China |
| 推荐引用方式 GB/T 7714 | Xu XQ,Yang HL,Yu HN,et al. The mastoparanogen from wasp[J]. PEPTIDES,2006,27(12):3053-3057. |
| APA | Xu XQ,Yang HL,Yu HN,Li JX,&Lai R[*].(2006).The mastoparanogen from wasp.PEPTIDES,27(12),3053-3057. |
| MLA | Xu XQ,et al."The mastoparanogen from wasp".PEPTIDES 27.12(2006):3053-3057. |
入库方式： OAI收割
来源：昆明动物研究所
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