中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 昆明动物研究所
  3. 昆明动物研究所
  4. 动物模型与人类重大疾病机理重点实验室
  5. 动物毒素室
Isolation and cDNA cloning of cholecystokinin from the skin of Rana nigrovittata

文献类型：期刊论文

作者Liu XH1; Wang YP2,3; Cheng LH1; Song YZ2,3; Lai R[*]1,2
刊名PEPTIDES
出版日期2007
卷号28期号:8页码:1540-1544
关键词amphibian Rana nigrovittata cholecystokinin skin-intestine-brain triangle peptide
ISSN号0196-9781
通讯作者rlai72@njau.edu.cn
合作状况其它
英文摘要Many neuroendocrine peptides that are distributed in amphibian gastrointestinal tract and central nervous system are also found in amphibian skins, and these peptides are classified into skin-gut-brain triangle peptides, such as bombesins, gastrin-releasing peptides. Cholecystokinins (CCKs) are neuroendocrine peptides known for their production in the gastrointestinal tract and central nervous system of mammalians. Several CCKs have been identified from two amphibians, Rana catesbeiana and Xenopus laevis. These amphibian CCKs are found to be express in brain and in the gastrointestinal tract, but not in skin. In the current report, a cholecystokinin (CCK) isoform was identified from skin secretions of the frog, Rana nigrovittata. Its amino acid sequence is RVDGNSDQKAVIGAMLAKDLQTRKAGSST-GRYAVLPNR PVIDPTHRINDRDYMGVTMDF, which is the same with that of CCK from R. catesbeiana. Four different cDNAs (GenBank accession nos. EF608063-6) encoding CCK precursors were cloned from the cDNA library of the skin of R. nigrovittata. The present data demonstrated that amphibian CCK could also be expressed in gastrointestinal tract, central nervous system and skin as other amphibian skin-gut-brain triangle peptides.
收录类别SCI
资助信息This work was supported by Yunnan Natural Science Foundation (2006C0011Z), 2006BAD06B07 from the Ministry of Science and Technology of the People’s Republic of China, KSCX2-YW-R-20 and KSCX2-YW-G-024 from Chinese Acad- emy of Sciences.
原文出处2007281540.pdf
语种英语
公开日期2010-08-24
源URL[http://159.226.149.42:8088/handle/152453/2505]  
专题昆明动物研究所_动物毒素室
昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位1.Key Laboratory of Microbiological Engineering of Agricultural Environment, Ministry of Agriculture, Life Sciences College of Nanjing Agricultural University, Nanjing, Jiangsu 210095, China
2.Biotoxin Department of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China
3.Graduate School of the Chinese Academy of Sciences, Beijing 100009, China
推荐引用方式
GB/T 7714		 Liu XH,Wang YP,Cheng LH,et al. Isolation and cDNA cloning of cholecystokinin from the skin of Rana nigrovittata[J]. PEPTIDES,2007,28(8):1540-1544.
APA Liu XH,Wang YP,Cheng LH,Song YZ,&Lai R[*].(2007).Isolation and cDNA cloning of cholecystokinin from the skin of Rana nigrovittata.PEPTIDES,28(8),1540-1544.
MLA Liu XH,et al."Isolation and cDNA cloning of cholecystokinin from the skin of Rana nigrovittata".PEPTIDES 28.8(2007):1540-1544.

入库方式： OAI收割

来源：昆明动物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。