Different Expression Profiles of Bioactive Peptides in Pelophylax nigromaculatus from Distinct Regions
文献类型：期刊论文
| 作者 | Song YZ[*]1; Ji SL1; Liu W1; Yu XY1; Meng QX1; Lai R[*]2,3 |
| 刊名 | BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
 |
| 出版日期 | 2013 |
| 卷号 | 77期号:5页码:1075-1079 |
| 关键词 | amphibian skin antimicrobial peptides antioxidant peptide different expression cDNA screening |
| 通讯作者 | uzhusong@kmust.edu.cn ; rlai@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Amphibian skin is an abundant repository of bioactive peptides, important components of the defensive system. The variability of the bioactive peptide repertoires of individual species remains unclear. In this study, dark-spotted frogs were collected from Kunming in Yunnan Province, China and Guiyang in Guizhou Province, China to determine whether the bioactive peptides in amphibian skin differ between the two regions. Eight-antimicrobial peptides and an antioxidant peptide were identified by screening of cDNA library. Among the identified peptides, three antimicrobial peptides (pelophylaxin-2GY, temporin-1GY, and temporin-1KM) and an antioxidant peptide (antioxidin-PN) are reported here for the first time. Nigrocin-1, nigrocin-2, and pelophylaxin-2 were expressed by frogs in both regions. Pelophylaxin-2GY and temporin-1GY were found only in the frogs from Guiyang, whereas antioxidin-PN, esculetin-1, esculetin-2, and temporin-1KM were found only in those from Kunming. This difference was confirmed by allele-specific RT-PCR. The bioactive peptides expressed clearly varied between these populations of the same species. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000320414900029 |
| 公开日期 | 2013-08-08 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7581]  |
| 专题 | 昆明动物研究所_动物毒素室 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Engineering Research Center for Molecular Diagnosis, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnam, China 2.Chinese Acad Sci, Kunming Inst Zool, Key Lab Anim Models & Human Dis Mech, Biotoxin Units, Kunming 650223, Yunnan, Peoples R China 3.Nanjing Agr Univ, Life Sci Coll, Nanjing 210095, Jiangsu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song YZ[*],Ji SL,Liu W,et al. Different Expression Profiles of Bioactive Peptides in Pelophylax nigromaculatus from Distinct Regions[J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,2013,77(5):1075-1079. |
| APA | Song YZ[*],Ji SL,Liu W,Yu XY,Meng QX,&Lai R[*].(2013).Different Expression Profiles of Bioactive Peptides in Pelophylax nigromaculatus from Distinct Regions.BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,77(5),1075-1079. |
| MLA | Song YZ[*],et al."Different Expression Profiles of Bioactive Peptides in Pelophylax nigromaculatus from Distinct Regions".BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77.5(2013):1075-1079. |
入库方式： OAI收割
来源：昆明动物研究所
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