A nerve growth factor from the venom of Chinese cobra (Naja naja atra) and its effects on male reproductive system in rats
文献类型：期刊论文
| 作者 | Xu TR; Wang WY; Lu QM; Xiong YL[*]; Huang YH; Meng QX; Li DS |
| 刊名 | COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY Part C
 |
| 出版日期 | 1999 |
| 卷号 | 124期号:2页码:149-156 |
| 关键词 | gossypol hormone isolation Naja naja atra nerve growth factor reproductive system testes venom |
| 通讯作者 | xutr@163.net |
| 合作状况 | 其它 |
| 英文摘要 | A nerve growth factor (NGF) was isolated from the venom of Chinese cobra (Naja naja ntr a) by ion exchange chromatography, gel filtration and fast protein liquid chromatography (FPLC). The N-terminal sequence of 22 amino acid residues was identical with other NGFs previously purified from the venom of the same genus. The NGF monomer molecular weight was estimated to be 13 500 by reducing SDS-PAGE and the isoelectric point was determined to be 7.2 by isoelectric focusing electrophoresis. NGF improved the epididymal sperm motility of male rats and increased the pregnancy rate and fetus number of mated female rats. The serum levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) of male rats administrated NGF + gossypol was lower than that of male rats administrated gossypol. Histological sections of testes and epididymides showed that NGF reduced the destructive effects of gossypol on rat testes. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10666]  |
| 专题 | 昆明动物研究所_动物毒素室 昆明动物研究所_其他 |
| 作者单位 | Kunming Institute of Zoology, Chinese Academy of Sciences Kunming 650223 PR China |
| 推荐引用方式 GB/T 7714 | Xu TR,Wang WY,Lu QM,et al. A nerve growth factor from the venom of Chinese cobra (Naja naja atra) and its effects on male reproductive system in rats[J]. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY Part C,1999,124(2):149-156. |
| APA | Xu TR.,Wang WY.,Lu QM.,Xiong YL[*].,Huang YH.,...&Li DS.(1999).A nerve growth factor from the venom of Chinese cobra (Naja naja atra) and its effects on male reproductive system in rats.COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY Part C,124(2),149-156. |
| MLA | Xu TR,et al."A nerve growth factor from the venom of Chinese cobra (Naja naja atra) and its effects on male reproductive system in rats".COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY Part C 124.2(1999):149-156. |
入库方式： OAI收割
来源：昆明动物研究所
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