SRY基因在人猿超科和旧大陆猴中具有不同的进化规律
文献类型：期刊论文
| 作者 | 王晓霞; 吕雪梅; 张亚平[*] |
| 刊名 | 遗传学报
 |
| 出版日期 | 2000 |
| 卷号 | 27期号:10页码:847-852 |
| ISSN号 | 0379-4172 |
| 关键词 | SRY基因 进化 正选择 人猿超科 旧大陆猴 |
| 中文摘要 | 通过PCR扩增、测序,得到了白臀叶猴和红面猴的SRY基因全序列。结合现有的灵长类其他物种序列进行分析,验证了HMG盒的保守性。通过构建系统发育树,比较旧大陆猴和人猿超科两个类群内和类群间HMG盒侧翼序列Ka/Ks的比率。 |
| 英文摘要 | The complete SRY gene of P. nemaeus and M. arctiodes were amplified by using PCR and sequenced. Combined with the same regions of other primate animals, sequence analysis confirmed the conservation of HMGbox. In molecular phylogenetic tree constructed, we made the Ka/Ks value pairwise comparison of HMGbox flanking sequences both intra- and inter- Hominoid and the Old World monkey. To our interest, the pairwise comparison of species in Hominoid suggested a higher Ka/Ks ratio than that in the Old World monkey or between the Old World monkey and marmoset, which showed existent of different pattern of evolution. In addition, in Hominoid Ka/Ks ratio for HMGbox sequences was obviously on the increase. The rate of nonsynonymous substitutions per nonsynonymous site is faster than that of synonymous substitutions per synonymous site in Hominoid (driven by positive directional selection). Our analysis suggested that it might be resulted from functional change of this gene and the system error or the close relationship among Hominoid species. It is also supposed that the positive selection was functioned at the beginning of the divergence of Hominoid species. |
| 资助信息 | 国家自然科学基金;中科院重大项目基金 |
| 收录类别 | 其他 |
| 原文出处 | 20002710847.pdf |
| 语种 | 中文 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/2307]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_细胞与分子进化开放实验室 |
| 作者单位 | 中国科学院昆明动物研究所细胞与分子进化开放研究实验室!昆明 650223 |
| 推荐引用方式 GB/T 7714 | 王晓霞,吕雪梅,张亚平[*]. SRY基因在人猿超科和旧大陆猴中具有不同的进化规律[J]. 遗传学报,2000,27(10):847-852. |
| APA | 王晓霞,吕雪梅,&张亚平[*].(2000).SRY基因在人猿超科和旧大陆猴中具有不同的进化规律.遗传学报,27(10),847-852. |
| MLA | 王晓霞,et al."SRY基因在人猿超科和旧大陆猴中具有不同的进化规律".遗传学报 27.10(2000):847-852. |
入库方式： OAI收割
来源：昆明动物研究所
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