Identification of monozygotic twin chimpanzees by microsatellite analysis
文献类型：期刊论文
| 作者 | Zhang YW1,2; Lawrance SK3; Ryder OA[*]1; Zhang YP2; Isaza R4 |
| 刊名 | AMERICAN JOURNAL OF PRIMATOLOGY
 |
| 出版日期 | 2000 |
| 卷号 | 52期号:2页码:101-106 |
| 关键词 | zygosity determination chimpanzee (Pan troglodytes) microsatellites |
| ISSN号 | 0275-2565 |
| 通讯作者 | oryder@ucsd.edu |
| 合作状况 | 其它 |
| 英文摘要 | Zygosity determination is important for epidemiological, biological, obstetric, and prognostic studies in both human and nonhuman primates. In this study, microsatellite loci were used to screen a pair of chimpanzee (Pan troglodytes) twins and their parents. The twins share identical alleles at all loci tested. The probability of dizygotic origin is estimated to be 2.9 x 10(-11). Even after excluding linkage of loci on the same chromosome, the probability is still low enough (3.7 x 10(-9)) to exclude dizygotic origin. MHC typing was also done on Patr-DRB and Patr-DQB loci and the twins share identical alleles at both loci, consistent with the microsatellite results. Together these results demonstrate a monozygotic origin for the chimp twins. Our results suggest that microsatellite analysis is a powerful method for zygosity determination, which can be screened reliably and efficiently. Am. J. Primatol. 52:101-106, 2000. (C) 2000 Wiley-Liss, Inc. |
| 收录类别 | SCI |
| 原文出处 | 200052101.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/3967]  |
| 专题 | 昆明动物研究所_分子进化基因组学 |
| 作者单位 | 1.Center for Reproduction of Endangered Species, Zoological Society of San Diego, San Diego, California 2.Kunming Institute of Zoology, Chinese Academy of Sciences, Yunnan, China 3.Department of Life and Earth Sciences, Otterbein College, Westerville, Ohio 4.Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas |
| 推荐引用方式 GB/T 7714 | Zhang YW,Lawrance SK,Ryder OA[*],et al. Identification of monozygotic twin chimpanzees by microsatellite analysis[J]. AMERICAN JOURNAL OF PRIMATOLOGY,2000,52(2):101-106. |
| APA | Zhang YW,Lawrance SK,Ryder OA[*],Zhang YP,&Isaza R.(2000).Identification of monozygotic twin chimpanzees by microsatellite analysis.AMERICAN JOURNAL OF PRIMATOLOGY,52(2),101-106. |
| MLA | Zhang YW,et al."Identification of monozygotic twin chimpanzees by microsatellite analysis".AMERICAN JOURNAL OF PRIMATOLOGY 52.2(2000):101-106. |
入库方式： OAI收割
来源：昆明动物研究所
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