Mitochondrial DNA sequence polymorphisms of five ethnic populations from northern China
文献类型：期刊论文
| 作者 | Kong QP1,2,3; Yao YG1,3; Liu, M4; Shen SP4; Chen C4; Zhu CL1; Palanichamy MG1; Zhang YP[*]1,2 |
| 刊名 | HUMAN GENETICS
 |
| 出版日期 | 2003 |
| 卷号 | 113期号:5页码:391-405 |
| ISSN号 | 0340-6717 |
| 通讯作者 | zhangyp1@263.net.cn |
| 合作状况 | 其它 |
| 英文摘要 | To study the mitochondrial DNA (mtDNA) polymorphisms in a total of 232 individuals from five ethnic populations (Daur, n=45; Ewenki, n=47; Korean, n=48; Mongolian, n=48; Oroqen, n=44) in northern China, we analyzed the control region sequences and typed for a number of characteristic mutations in coding regions (especially the region 14576-16047), by direct sequencing or restriction-fragment-length-polymorphism (RFLP) analysis. With the exception of 14 individuals belonging to the European-specific haplogroups R2, H, J, and T, the mtDNAs considered could be assigned into the East Asian-specific haplogroups described recently. The polymorphisms in cytochrome b sequence were found to be very informative for defining or supporting the haplogroups status of East Asian mtDNAs in addition to the reported regions 10171-10659 and 14055-14590 in our previous study. The haplogroup distribution frequencies varied in the five ethnic populations, but in general they all harbored a large amount of north-prevalent haplogroups, such as D, G, C, and Z, and thus were in agreement with their ethnohistory of northern origin. The two populations (Ewenki and Oroqen) with small population census also show concordant features in their matrilineal genetic structures, with lower genetic diversities observed. |
| 收录类别 | SCI |
| 资助信息 | The work was supported by Natural Science Foundation of China (NSFC) and Natural Science Foundation of Yunnan Province. |
| 原文出处 | 2003113391.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4083]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_分子人类学 昆明动物研究所_重大疾病机理的遗传学 昆明动物研究所_细胞与分子进化重点实验室 |
| 作者单位 | 1.Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223 Kunming, China 2.Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, 650091 Kunming, China 3.Graduate School of the Chinese Academy of Sciences, 100039 Beijing, China 4.Department of Pathology, Baotou Medical College, 014010 Baotou, Inner Mongolia, China |
| 推荐引用方式 GB/T 7714 | Kong QP,Yao YG,Liu, M,et al. Mitochondrial DNA sequence polymorphisms of five ethnic populations from northern China[J]. HUMAN GENETICS,2003,113(5):391-405. |
| APA | Kong QP.,Yao YG.,Liu, M.,Shen SP.,Chen C.,...&Zhang YP[*].(2003).Mitochondrial DNA sequence polymorphisms of five ethnic populations from northern China.HUMAN GENETICS,113(5),391-405. |
| MLA | Kong QP,et al."Mitochondrial DNA sequence polymorphisms of five ethnic populations from northern China".HUMAN GENETICS 113.5(2003):391-405. |
入库方式： OAI收割
来源：昆明动物研究所
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