Evolutionary implications of avian infectious Bronchitis Virus (AIBV) analysis
文献类型：期刊论文
| 作者 | Shi P1,2; Yu L2; Fu YX3; Huang JF1; Zhang KQ2; Zhang YP[*]1,2 |
| 刊名 | CELL RESEARCH
 |
| 出版日期 | 2006 |
| 卷号 | 16期号:3页码:323-327 |
| 关键词 | Avian Infectious Bronchitis Virus SARS Coronavirus positive selection adaptive evolution vaccine de- velopment |
| ISSN号 | 1001-0602 |
| 通讯作者 | zhangyp1@263.net.cn |
| 合作状况 | 其它 |
| 英文摘要 | For developing efficient vaccines, it is essential to identify which amino acid changes are most important to the survival of the virus. We investigate the amino acid substitution features in the Avian Infectious Bronchitis Virus (AIBV) antigenic domain of a vaccine serotype (DE072) and a virulent viral strain (GA98) to better understand adaptive evolution of AIBV. In addition, the SARS Coronavirus (SARS-CoV) was also analyzed in the same way. It is interesting to find that extreme comparability exists between AIBV and SARS in amino acid substitution pattern. It suggests that amino acid changes that result in overall shift of residue charge and polarity should be paid special attention to during the development of vaccines. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by special grants from Yunnan Province. |
| 原文出处 | 200616323.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4211]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_结构生物信息学 昆明动物研究所_进化与功能基因组学 昆明动物研究所_细胞与分子进化开放实验室 |
| 作者单位 | 1.Laboratory of Cellular and Molecular Evolution, and Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2.Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091, China 3.Human Genetics Center, University of Texas at Houston, Houston, Texas 77030, USA |
| 推荐引用方式 GB/T 7714 | Shi P,Yu L,Fu YX,et al. Evolutionary implications of avian infectious Bronchitis Virus (AIBV) analysis[J]. CELL RESEARCH,2006,16(3):323-327. |
| APA | Shi P,Yu L,Fu YX,Huang JF,Zhang KQ,&Zhang YP[*].(2006).Evolutionary implications of avian infectious Bronchitis Virus (AIBV) analysis.CELL RESEARCH,16(3),323-327. |
| MLA | Shi P,et al."Evolutionary implications of avian infectious Bronchitis Virus (AIBV) analysis".CELL RESEARCH 16.3(2006):323-327. |
入库方式： OAI收割
来源：昆明动物研究所
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