Evolution of cd59 gene in mammals
文献类型：期刊论文
| 作者 | Gong YY1,2; Peng MS1,2; Zhou WP1,3,4; Zhang YP[*]1,4 |
| 刊名 | SCIENCE IN CHINA SERIES C-LIFE SCIENCES
 |
| 出版日期 | 2007 |
| 卷号 | 50期号:6页码:773-779 |
| 关键词 | cd59 evolution positive selection |
| ISSN号 | 1006-9305 |
| 通讯作者 | zhangyp1@263.net.cn |
| 合作状况 | 其它 |
| 英文摘要 | The CD59-coding sequences were obtained from 5 mammals by PCR and BLAST, and combined with the available sequences in GenBank, the nucleotide substitution rates of mammalian cd59 were calculated. Results of synonymous and nonsynonymous substitution rates revealed that cd59 experienced negative selection in mammals overall. Four sites experiencing positive selection were found by using "site-specific" model in PAML software. These sites were distributed on the molecular surface, of which 2 sites located in the key functional domain. Furthermore, "branch-site-specific" model detected 1 positive site in cd59a and cd59b lineages which underwent accelerated evolution caused by positive selection after gene duplication in mouse. |
| 收录类别 | SCI |
| 资助信息 | Supported by the National Basic Research Program of China (973 Program, Grant No. 2007CB411600), the National Natural Science Foundation of China (Grant Nos. 30621092 and 30430110), and Bureau of Science and Technology of Yunnan Province, China |
| 原文出处 | 200750773.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4231]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2.Graduate University of the Chinese Academy of Sciences, Beijing 100049, China; 3.Molecular and Cell Biology, University of Science and Technology of China, Hefei 230026, China; 4.Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, Kunming 650091, China |
| 推荐引用方式 GB/T 7714 | Gong YY,Peng MS,Zhou WP,et al. Evolution of cd59 gene in mammals[J]. SCIENCE IN CHINA SERIES C-LIFE SCIENCES,2007,50(6):773-779. |
| APA | Gong YY,Peng MS,Zhou WP,&Zhang YP[*].(2007).Evolution of cd59 gene in mammals.SCIENCE IN CHINA SERIES C-LIFE SCIENCES,50(6),773-779. |
| MLA | Gong YY,et al."Evolution of cd59 gene in mammals".SCIENCE IN CHINA SERIES C-LIFE SCIENCES 50.6(2007):773-779. |
入库方式： OAI收割
来源：昆明动物研究所
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