Insight into human sex ratio imbalance: the more boys born, the more infertile men
文献类型：期刊论文
| 作者 | Cheng HH1; Shang X1; He Y1; Zhang T1; Zhang YP2; Zhou RJ[*]1 |
| 刊名 | REPRODUCTIVE BIOMEDICINE ONLINE
 |
| 出版日期 | 2007 |
| 卷号 | 15期号:5页码:487-494 |
| 关键词 | adaptation evolution male infertility population |
| ISSN号 | 1472-6483 |
| 通讯作者 | rjzhou@whu.edu.cn |
| 英文摘要 | This study investigated, through large-scale statistical analysis of the global population, whether the human sex ratio is skewing worldwide, and if so, why and how it shifts, and the impact of any shift on human reproduction. A significant imbalance of the sex ratio was observed in the whole human population, resulting in a vicious circle where the more boys born, the more infertile men occur as a consequence of the adjustment of the human sex ratio. It is proposed that both accelerated degeneration of the Y chromosome and dynamically differential fertilization of the egg by the X- and Y-bearing spermatozoa may contribute to the changing structure of the human population, suggesting a potential selection pressure favouring an alternative sex-determining/differentiation system for the human species: the DMRT] gene on the autosome may tend to replace the SRY gene on tile Y chromosome as a master sex-determining gene during evolution. These viewpoints may open a debate on the future of the human race, and assist in guiding diagnostic, prognostic and preventive treatments of human infertility and in defining population policy. |
| 资助信息 | The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. |
| 原文出处 | 200715487.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4233]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_细胞与分子进化开放实验室 |
| 作者单位 | 1.Department of Genetics and Centre for Developmental Biology, College of Life Sciences, Wuhan University, Wuhan 430072 2.Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, People’s Republic of China |
| 推荐引用方式 GB/T 7714 | Cheng HH,Shang X,He Y,et al. Insight into human sex ratio imbalance: the more boys born, the more infertile men[J]. REPRODUCTIVE BIOMEDICINE ONLINE,2007,15(5):487-494. |
| APA | Cheng HH,Shang X,He Y,Zhang T,Zhang YP,&Zhou RJ[*].(2007).Insight into human sex ratio imbalance: the more boys born, the more infertile men.REPRODUCTIVE BIOMEDICINE ONLINE,15(5),487-494. |
| MLA | Cheng HH,et al."Insight into human sex ratio imbalance: the more boys born, the more infertile men".REPRODUCTIVE BIOMEDICINE ONLINE 15.5(2007):487-494. |
入库方式： OAI收割
来源：昆明动物研究所
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