Adaptive Evolution of Digestive RNASE1 Genes in Leaf-Eating Monkeys Revisited: New Insights from Ten Additional Colobines
文献类型：期刊论文
| 作者 | Yu L[*]1; Wang XY1; Jin W1; Luan PT1; Ting N2; Zhang YP3 |
| 刊名 | MOLECULAR BIOLOGY AND EVOLUTION
 |
| 出版日期 | 2010 |
| 卷号 | 27期号:1页码:121-131 |
| 关键词 | RNASE1 colobines adaptive evolution gene conversion independent duplication |
| ISSN号 | 0737-4038 |
| 通讯作者 | yuli1220@yahoo.com.cn |
| 合作状况 | 其它 |
| 英文摘要 | Pancreatic RNase genes implicated in the adaptation of the colobine monkeys to leaf eating have long intrigued evolutionary biologists since the identification of a duplicated RNASE1 gene with enhanced digestive efficiencies in Pygathrix nemaeus. The recent emergence of two contrasting hypotheses, that is, independent duplication and one-duplication event hypotheses, make it into focus again. Current understanding of Colobine RNASE1 gene evolution of colobine monkeys largely depends on the analyses of few colobine species. The present study with more intensive taxonomic and character sampling not only provides a clearer picture of Colobine RNASE1 gene evolution but also allows to have a more thorough understanding about the molecular basis underlying the adaptation of Colobinae to the unique leaf-feeding lifestyle. The present broader and detailed phylogenetic analyses yielded two important findings: 1) All trees based on the analyses of coding, noncoding, and both regions provided consistent evidence, indicating RNASE1 duplication occurred after Asian and African colobines speciation, that is, independent duplication hypothesis; 2) No obvious evidence of gene conversion in RNASE1 gene was found, favoring independent evolution of Colobine RNASE1 gene duplicates. The conclusion drawn from previous studies that gene conversion has played a significant role in the evolution of Colobine RNASE1 was not supported. Our selective constraint analyses also provided interesting insights, with significant evidence of positive selection detected on ancestor lineages leading to duplicated gene copies. The identification of a handful of new adaptive sites and amino acid changes that have not been characterized previously also provide a necessary foundation for further experimental investigations of RNASE1 functional evolution in Colobinae. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by grants from the State Key Basic Research and Develop- ment Plan (2007CB411600) and National Natural Science Foundation of China (U0836603, 30621092). |
| 原文出处 | 2010271121.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4373]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Laboratory for Conservation and Utilization of Bio-resource and Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming, China 2.Anthropology Program, City University of New York Graduate Center 3.State Key Laboratory of Genetic Resources and Evolution and Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Kunming, China |
| 推荐引用方式 GB/T 7714 | Yu L[*],Wang XY,Jin W,et al. Adaptive Evolution of Digestive RNASE1 Genes in Leaf-Eating Monkeys Revisited: New Insights from Ten Additional Colobines[J]. MOLECULAR BIOLOGY AND EVOLUTION,2010,27(1):121-131. |
| APA | Yu L[*],Wang XY,Jin W,Luan PT,Ting N,&Zhang YP.(2010).Adaptive Evolution of Digestive RNASE1 Genes in Leaf-Eating Monkeys Revisited: New Insights from Ten Additional Colobines.MOLECULAR BIOLOGY AND EVOLUTION,27(1),121-131. |
| MLA | Yu L[*],et al."Adaptive Evolution of Digestive RNASE1 Genes in Leaf-Eating Monkeys Revisited: New Insights from Ten Additional Colobines".MOLECULAR BIOLOGY AND EVOLUTION 27.1(2010):121-131. |
入库方式： OAI收割
来源：昆明动物研究所
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