中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Inland post-glacial dispersal in East Asia revealed by mitochondrial haplogroup M9a'b

文献类型:期刊论文

作者Peng MS1,2,6; Palanichamy MG3; Yao YG4; Mitra B3; Cheng YT1,2,6; Zhao M1,2,6; Liu J3; Wang HW3; Pan H1,2,6; Wang WZ1,2,6
刊名BMC BIOLOGY
出版日期2011
卷号9期号:X页码:e2
通讯作者kongqp@yahoo.com.cn ; zhangyp@mail.kiz.ac.cn
合作状况其它
英文摘要Background: Archaeological studies have revealed a series of cultural changes around the Last Glacial Maximum in East Asia; whether these changes left any signatures in the gene pool of East Asians remains poorly indicated. To achieve deeper insights into the demographic history of modern humans in East Asia around the Last Glacial Maximum, we extensively analyzed mitochondrial DNA haplogroup M9a'b, a specific haplogroup that was suggested to have some potential for tracing the migration around the Last Glacial Maximum in East Eurasia. Results: A total of 837 M9a'b mitochondrial DNAs (583 from the literature, while the remaining 254 were newly collected in this study) pinpointed from over 28,000 subjects residing across East Eurasia were studied here. Fifty-nine representative samples were further selected for total mitochondrial DNA sequencing so we could better understand the phylogeny within M9a'b. Based on the updated phylogeny, an extensive phylogeographic analysis was carried out to reveal the differentiation of haplogroup M9a'b and to reconstruct the dispersal histories. Conclusions: Our results indicated that southern China and/or Southeast Asia likely served as the source of some post-Last Glacial Maximum dispersal(s). The detailed dissection of haplogroup M9a'b revealed the existence of an inland dispersal in mainland East Asia during the post-glacial period. It was this dispersal that expanded not only to western China but also to northeast India and the south Himalaya region. A similar phylogeographic distribution pattern was also observed for haplogroup F1c, thus substantiating our proposition. This inland post-glacial dispersal was in agreement with the spread of the Mesolithic culture originating in South China and northern Vietnam.
收录类别SCI
资助信息This study was supported by grants from the National Natural Science Foundation of China (30621092 and 30900797), and the Bureau of Science and Technology of Yunnan Province (2009CI119).
语种英语
公开日期2011-03-14
源URL[http://159.226.149.42:8088/handle/353002/6573]  
专题昆明动物研究所_分子进化基因组学
昆明动物研究所_动物模型与人类重大疾病机理重点实验室
昆明动物研究所_遗传资源与进化国家重点实验室
昆明动物研究所_分子人类学
昆明动物研究所_重大疾病机理的遗传学
昆明动物研究所_生命条形码中心
作者单位1.Graduate School of the Chinese Academy of Sciences, Beijing, PR China
2.KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, China
3.Laboratory for Conservation and Utilization of Bio- resources, Yunnan University, Kunming, China
4.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, China
5.Cellular Immunology Laboratory, Department of Zoology, University of North Bengal, Siliguri, India. 6 Graduate School of the Chinese Academy of Sciences, Beijing, China
6.Graduate School of the Chinese Academy of Sciences, Beijing, China
推荐引用方式
GB/T 7714
Peng MS,Palanichamy MG,Yao YG,et al. Inland post-glacial dispersal in East Asia revealed by mitochondrial haplogroup M9a'b[J]. BMC BIOLOGY,2011,9(X):e2.
APA Peng MS.,Palanichamy MG.,Yao YG.,Mitra B.,Cheng YT.,...&Zhang YP[*].(2011).Inland post-glacial dispersal in East Asia revealed by mitochondrial haplogroup M9a'b.BMC BIOLOGY,9(X),e2.
MLA Peng MS,et al."Inland post-glacial dispersal in East Asia revealed by mitochondrial haplogroup M9a'b".BMC BIOLOGY 9.X(2011):e2.

入库方式: OAI收割

来源:昆明动物研究所

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