Eukaryotic origin of a metabolic pathway in virus by horizontal gene transfer
文献类型：期刊论文
| 作者 | Wu DD1,3; Zhang YP[*]1,2 |
| 刊名 | GENOMICS
 |
| 出版日期 | 2011 |
| 卷号 | 98期号:5页码:367-369 |
| 关键词 | Horizontal gene transfer Hz-1 virus |
| 通讯作者 | zhangyp@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Horizontal gene transfer, the movement of genetic materials across the normal mating barriers between organisms occurs frequently and contributes significantly to the evolution of both eukaryotic and prokaryotic genomes. However, few concurrent transfers of functionally related genes implemented in a pathway from eukaryotes to prokaryotes are observed. Here, we did phylogenetic analyses to support that the genes, i.e. dihydrofolate reductase, glycine hydroxymethyltransferase, and thymidylate synthase involved in thymidylate metabolism, in Hz-1 virus were obtained from insect genome recently by independent horizontal gene transfers. In addition, five other related genes in nucleotide metabolism show evidences of horizontal gene transfers. These genes demonstrate similar expression pattern, and they may have formatted a functionally related pathway (e.g. thymidylate synthesis, and DNA replication) in Hz-1 virus. In conclusion, we provide an example of horizontal gene transfer of functionally related genes in a pathway to prokaryote from eukaryote. |
| 资助信息 | This work was supported by grants from the National Basic Research Program of China (973 Program, 2007CB411600), the National Natural Science Foundation of China (30621092, 30430110), and Bureau of Science and Technology of Yunnan Province. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2011-12-08 |
| 源URL | [http://159.226.149.42:8088/handle/353002/6830]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 昆明动物研究所_进化与发育转录组学 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 2.Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091, China 3.Graduate School of the Chinese Academy of Sciences, Beijing, China |
| 推荐引用方式 GB/T 7714 | Wu DD,Zhang YP[*]. Eukaryotic origin of a metabolic pathway in virus by horizontal gene transfer[J]. GENOMICS,2011,98(5):367-369. |
| APA | Wu DD,&Zhang YP[*].(2011).Eukaryotic origin of a metabolic pathway in virus by horizontal gene transfer.GENOMICS,98(5),367-369. |
| MLA | Wu DD,et al."Eukaryotic origin of a metabolic pathway in virus by horizontal gene transfer".GENOMICS 98.5(2011):367-369. |
入库方式： OAI收割
来源：昆明动物研究所
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