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The genomics of selection in dogs and the parallel evolution between dogs and humans
文献类型：期刊论文
| 作者 | Wang GD1; Zhai WW2; Yang HC1,3; Fan RX4; Cao X1; Zhong L4; Wang L4; Liu F1; Wu H4; Cheng LG5 |
| 刊名 | NATURE COMMUNICATIONS
 |
| 出版日期 | 2013 |
| 卷号 | 4期号:X页码:e1860 |
| 通讯作者 | ciwu@uchicago.edu ; zhangyp@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | The genetic bases of demographic changes and artificial selection underlying domestication are of great interest in evolutionary biology. Here we perform whole-genome sequencing of multiple grey wolves, Chinese indigenous dogs and dogs of diverse breeds. Demographic analysis show that the split between wolves and Chinese indigenous dogs occurred 32,000 years ago and that the subsequent bottlenecks were mild. Therefore, dogs may have been under human selection over a much longer time than previously concluded, based on molecular data, perhaps by initially scavenging with humans. Population genetic analysis identifies a list of genes under positive selection during domestication, which overlaps extensively with the corresponding list of positively selected genes in humans. Parallel evolution is most apparent in genes for digestion and metabolism, neurological process and cancer. Our study, for the first time, draws together humans and dogs in their recent genomic evolution. |
| 收录类别 | SCI |
| 资助信息 | This work is supported by grants from National Natural Science Foundation of China (91231108), 973 program (2013CB835200), Bureau of Science and Technology of Yunnan Province, and Chinese Academy of Sciences. Peter Savolainen is a Royal Swedish Academy of Sciences Research Fellow supported by a grant from the Knut and Alice Wallenberg Foundation. |
| 语种 | 英语 |
| WOS记录号 | WOS:000320589900056 |
| 公开日期 | 2013-09-04 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7625]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, No. 32 Jiaochang Donglu, Kunming 650223, China 2.Center for Computational Biology and Laboratory of Disease Genomics and Individualized Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, No. 1 Beichen West Road, Chaoyang District, Beijing 100101, China 3.Department of Molecular and Cell Biology, School of Life Sciences, University of Science and Technology of China, No. 96 JinZhai Road, Hefei 230026, China 4.Laboratory for Conservation and Utilization of Bio- resources, Yunnan University, No. 2 Cuihu Beilu, Kunming 650091, China. 5 Kunming Police Dog Base, Ministry of Public Security, Heilongtan, Kunming 650204, China 5.Kunming Police Dog Base, Ministry of Public Security, Heilongtan, Kunming 650204, China 6.Severtsov Institute of Ecology and Evolution, Russian Academy of Science, Leninskiy prospect, 33, Moscow 119071, Russia 7.Department of Vertebrate Zoology, Faculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory, Moscow 119991, Russia 8.Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King’s College Circle, Toronto, Ontario, Canada M5S 1A8 9.School of Biotechnology, KTH Royal Institute of Technology, Science for Life Laboratory, Tomtebodava ¨gen 23A, SE-171 21 Solna, Sweden. 10.Department of Ecology and Evolution, University of Chicago, 1101 E 57th Street, Chicago, Illinois 60637, USA |
| 推荐引用方式 GB/T 7714 | Wang GD,Zhai WW,Yang HC,et al. The genomics of selection in dogs and the parallel evolution between dogs and humans[J]. NATURE COMMUNICATIONS,2013,4(X):e1860. |
| APA | Wang GD.,Zhai WW.,Yang HC.,Fan RX.,Cao X.,...&Zhang YP[*].(2013).The genomics of selection in dogs and the parallel evolution between dogs and humans.NATURE COMMUNICATIONS,4(X),e1860. |
| MLA | Wang GD,et al."The genomics of selection in dogs and the parallel evolution between dogs and humans".NATURE COMMUNICATIONS 4.X(2013):e1860. |
入库方式： OAI收割
来源：昆明动物研究所
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