Parallel evolution of IDH2 gene in cetaceans, primates and bats
文献类型:期刊论文
作者 | Ai WM1; Chen SB1; Chen X1,5; Shen XJ2; Shen YY[*]2,3,4 |
刊名 | FEBS LETTERS
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出版日期 | 2014 |
卷号 | 588期号:3页码:450-454 |
关键词 | Dolphin Bat Adaptive evolution Energy metabolism Parallel evolution |
通讯作者 | shenyy@mail.kiz.ac.cn |
合作状况 | 其它 |
英文摘要 | Cetaceans and primates both have large brains that require large amounts of aerobic energy metabolism. In bats, the cost of flight makes locomotion energetically demanding. These mammalian groups may represent three independent evolutionary origins of an energy-demanding lifestyle in mammals. IDH2 encodes an enzyme in the tricarboxylic acid cycle in the mitochondrion, which plays a key role in aerobic energy metabolism. In this study, we cloned and sequenced this gene in two cetaceans, and 19 bat species, and compared the data with available primate sequences to test its evolution. We found significant signals of parallel evolution in this gene among these three groups. Parallel evolution of this gene may reflect their parallel evolution towards a higher demand for energy. |
收录类别 | SCI |
资助信息 | This work was supported by Grants from the National Natural Science Foundation of China (No. 31172080). |
语种 | 英语 |
WOS记录号 | WOS:000329976800011 |
公开日期 | 2014-02-14 |
源URL | [http://159.226.149.42:8088/handle/152453/7800] ![]() |
专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 |
作者单位 | 1.Department of Marine Science, School of Life Science, Wenzhou Medical College, Wenzhou 325035, China 2.Joint Influenza Research Centre (SUMC/HKU), Shantou University Medical College, Shantou 515041, China 3.State Key Laboratory of Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong 4.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China 5.Guangxi Key Lab for Mangrove Conservation and Utilization, Guangxi Mangrove Research Center, Beihai 536000, China |
推荐引用方式 GB/T 7714 | Ai WM,Chen SB,Chen X,et al. Parallel evolution of IDH2 gene in cetaceans, primates and bats[J]. FEBS LETTERS,2014,588(3):450-454. |
APA | Ai WM,Chen SB,Chen X,Shen XJ,&Shen YY[*].(2014).Parallel evolution of IDH2 gene in cetaceans, primates and bats.FEBS LETTERS,588(3),450-454. |
MLA | Ai WM,et al."Parallel evolution of IDH2 gene in cetaceans, primates and bats".FEBS LETTERS 588.3(2014):450-454. |
入库方式: OAI收割
来源:昆明动物研究所
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