Advances in research on Shadoo, shadow of prion protein
文献类型：期刊论文
| 作者 | Wang SQ1; Zhao H[*]1; Zhang YP1,2 |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2014 |
| 卷号 | 59期号:9页码:821-827 |
| 关键词 | Shadoo Prion Prion disease Function Polymorphism Expression |
| 通讯作者 | zhaohui@ynu.edu.cn |
| 英文摘要 | Prion plays a central role in the pathogenesis of transmissible spongiform encephalopathies, also known as prion diseases. However, the biology of the protein and the pathophysiology of these diseases remain largely unknown. It has been speculated that additional factor or factors may be involved in the pathogenesis of prion diseases. Recently, a PrP-like protein, recognized as shadow of prion protein (Shadoo, Sho), is thought to be an interesting candidate factor because both the prion protein and Sho have been shown to have overlapping expression patterns and shared functions. Therefore, extensive study of Sho may advance our understanding of the enigmatical biology of prion and prion diseases. In this review, recent studies on Sho associated with prion diseases and functions are summarized. These studies have demonstrated the functional importance of Sho, and they further need to investigate its biological roles in prion diseases. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the National Natural Science Foundation of China (31060302, 31260032) and the Natural Science Foundation of Yunnan Province (2010CD010). |
| 语种 | 英语 |
| WOS记录号 | WOS:000332422300001 |
| 公开日期 | 2014-04-04 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7831]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091, China 2.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China |
| 推荐引用方式 GB/T 7714 | Wang SQ,Zhao H[*],Zhang YP. Advances in research on Shadoo, shadow of prion protein[J]. CHINESE SCIENCE BULLETIN,2014,59(9):821-827. |
| APA | Wang SQ,Zhao H[*],&Zhang YP.(2014).Advances in research on Shadoo, shadow of prion protein.CHINESE SCIENCE BULLETIN,59(9),821-827. |
| MLA | Wang SQ,et al."Advances in research on Shadoo, shadow of prion protein".CHINESE SCIENCE BULLETIN 59.9(2014):821-827. |
入库方式： OAI收割
来源：昆明动物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。