Domestication of the Dog from the Wolf Was Promoted by Enhanced Excitatory Synaptic Plasticity: A
文献类型：期刊论文
| 作者 | Li Y1,2; Wang GD1,2; Wang MS1,2,3; Irwin DM1,4,5; Wu DD[*]1,2; Zhang YP[*]1,2 |
| 刊名 | GENOME BIOLOGY AND EVOLUTION
 |
| 出版日期 | 2014 |
| 卷号 | 6期号:11页码:3115-3121 |
| 关键词 | gray wolf learning self-domestication memory fear response |
| 通讯作者 | wudongdong@mail.kiz.ac.cn ; zhangyp@ mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Dogs shared a much closer relationship with humans than any other domesticated animals, probably due to their unique social cognitive capabilities, which were hypothesized to be a by-product of selection for tameness toward humans. Here, we demonstrate that genes involved in glutamate metabolism, which account partially for fear response, indeed show the greatest population differentiation by whole-genome comparison of dogs and wolves. However, the changing direction of their expression supports a role in increasing excitatory synaptic plasticity in dogs rather than reducing fear response. Because synaptic plasticity are widely believed to be cellular correlates of learning and memory, this change may alter the learning and memory abilities of ancient scavenging wolves, weaken the fear reaction toward humans, and prompt the initial interspecific contact. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by grants from the National Natural Science Foundation of China (31321002, 91231108, 31123005), and the 973 program (2013CB835200). |
| 语种 | 英语 |
| 公开日期 | 2015-02-02 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8244]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 昆明动物研究所_进化与发育转录组学 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 2.Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, China 3.University of Chinese Academy of Sciences, Beijing, China 4.Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada 5.Banting and Best Diabetes Centre, University of Toronto, Ontario, Canada |
| 推荐引用方式 GB/T 7714 | Li Y,Wang GD,Wang MS,et al. Domestication of the Dog from the Wolf Was Promoted by Enhanced Excitatory Synaptic Plasticity: A[J]. GENOME BIOLOGY AND EVOLUTION,2014,6(11):3115-3121. |
| APA | Li Y,Wang GD,Wang MS,Irwin DM,Wu DD[*],&Zhang YP[*].(2014).Domestication of the Dog from the Wolf Was Promoted by Enhanced Excitatory Synaptic Plasticity: A.GENOME BIOLOGY AND EVOLUTION,6(11),3115-3121. |
| MLA | Li Y,et al."Domestication of the Dog from the Wolf Was Promoted by Enhanced Excitatory Synaptic Plasticity: A".GENOME BIOLOGY AND EVOLUTION 6.11(2014):3115-3121. |
入库方式： OAI收割
来源：昆明动物研究所
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