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Whole-genome sequence of the Tibetan frog Nanorana parkeri and the comparative evolution of tetrapod genomes
文献类型：期刊论文
| 作者 | Sun YB1; Xiong ZJ2,3,4; Xiang XY3,4,5,6; Liu SP2,3,4,5; Zhou WW2,3,4,6; Tu XL1,7; Zhong L8; Wang L8; Wu DD1; Zhang BL1,8 |
| 刊名 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
 |
| 出版日期 | 2015 |
| 卷号 | 112期号:11页码:E1257-E1262 |
| 关键词 | de novo genome transposable elements chromosome rearrangement highly conserved element |
| 通讯作者 | dhillis@austin.utexas.edu, chej@ mail.kiz.ac.cn, wangjun30@gmail.com ; zhangyp@mail.kiz.ac.cn. |
| 合作状况 | 其它 |
| 英文摘要 | The development of efficient sequencing techniques has resulted in large numbers of genomes being available for evolutionary studies. However, only one genome is available for all amphibians, that of Xenopus tropicalis, which is distantly related from the majority of frogs. More than 96% of frogs belong to the Neobatrachia, and no genome exists for this group. This dearth of amphibian genomes greatly restricts genomic studies of amphibians and, more generally, our understanding of tetrapod genome evolution. To fill this gap, we provide the de novo genome of a Tibetan Plateau frog, Nanorana parkeri, and compare it to that of X. tropicalis and other vertebrates. This genome encodes more than 20,000 protein-coding genes, a number similar to that of Xenopus. Although the genome size of Nanorana is considerably larger than that of Xenopus (2.3 vs. 1.5 Gb), most of the difference is due to the respective number of transposable elements in the two genomes. The two frogs exhibit considerable conserved whole-genome synteny despite having diverged approximately 266 Ma, indicating a slow rate of DNA structural evolution in anurans. Multigenome synteny blocks further show that amphibians have fewer interchromosomal rearrangements than mammals but have a comparable rate of intrachromosomal rearrangements. Our analysis also identifies 11 Mb of anuran-specific highly conserved elements that will be useful for comparative genomic analyses of frogs. The Nanorana genome offers an improved understanding of evolution of tetrapod genomes and also provides a genomic reference for other evolutionary studies. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by Strategic Priority Research Program (B) Grant XDB13020200 of the Chinese Academy of Sciences (CAS), National Natural Science Foundation of China Grant 91431105, Key Research Program of CAS Grant KJZD-EW-L07, the Animal Branch of the Germplasm Bank of Wild Species of CAS (the Large Research Infrastructure Funding), and Shenzhen Municipal Government of China Grant CXB201108250096A. |
| 语种 | 英语 |
| WOS记录号 | WOS:000351060000014 |
| 公开日期 | 2015-04-10 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8290]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 昆明动物研究所_进化与发育转录组学 昆明动物研究所_两栖爬行类多样性与进化 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 2.China National GeneBank 3.Shenzhen Key Laboratory of Transomics Biotechnologies, d BGI-Shenzhen, Shenzhen 518083, China 4.BGI-Shenzhen, Shenzhen 518083, China 5.College of Life Sciences, Sichuan University, Chengdu 610064, China 6.School of Bioscience and Biotechnology, South China University of Technology, Guangzhou 510641, China 7.Kunming College of Life Science, Chinese Academy of Sciences, Kunming 650204, China 8.Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091, China 9.Centre for Social Evolution, Department of Biology, University of Copenhagen, DK-2100 Copenhagen, Denmark 10.Department of Laboratory Medicine and Pathobiology and k Banting and Best Diabetes Centre, University of Toronto, Toronto, ON, M5S 1A8, Canada |
| 推荐引用方式 GB/T 7714 | Sun YB,Xiong ZJ,Xiang XY,et al. Whole-genome sequence of the Tibetan frog Nanorana parkeri and the comparative evolution of tetrapod genomes[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2015,112(11):E1257-E1262. |
| APA | Sun YB.,Xiong ZJ.,Xiang XY.,Liu SP.,Zhou WW.,...&Wang J[*].(2015).Whole-genome sequence of the Tibetan frog Nanorana parkeri and the comparative evolution of tetrapod genomes.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,112(11),E1257-E1262. |
| MLA | Sun YB,et al."Whole-genome sequence of the Tibetan frog Nanorana parkeri and the comparative evolution of tetrapod genomes".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112.11(2015):E1257-E1262. |
入库方式： OAI收割
来源：昆明动物研究所
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