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DoGSD: the dog and wolf genome SNP database

文献类型:期刊论文

作者Bai B1,2,4; Zhao WM3; Tang BX3,5; Wang YQ3; Wang L1; Zhang Z5; Yang HC3,4,6; Liu YH1; Zhu JW3; Irwin DM2,7
刊名NUCLEIC ACIDS RESEARCH
出版日期2015
卷号43期号:Database issue页码:D777-D783
通讯作者wanggd@mail.kiz.ac.cn ; zhangyp@@mail.kiz.ac.cn
合作状况其它
英文摘要The rapid advancement of next-generation sequencing technology has generated a deluge of genomic data from domesticated dogs and their wild ancestor, grey wolves, which have simultaneously broadened our understanding of domestication and diseases that are shared by humans and dogs. To address the scarcity of single nucleotide polymorphism (SNP) data provided by authorized databases and to make SNP data more easily/friendly usable and available, we propose DoGSD (http://dogsd.big.ac.cn), the first canidae-specific database which focuses on whole genome SNP data from domesticated dogs and grey wolves. The DoGSD is a web-based, open-access resource comprising similar to 19 million high-quality whole-genome SNPs. In addition to the dbSNP data set (build 139), DoGSD incorporates a comprehensive collection of SNPs from two newly sequenced samples (1 wolf and 1 dog) and collected SNPs from three latest dog/wolf genetic studies (7 wolves and 68 dogs), which were taken together for analysis with the population genetic statistics, Fst. In addition, DoGSD integrates some closely related information including SNP annotation, summary lists of SNPs located in genes, synonymous and non-synonymous SNPs, sampling location and breed information. All these features make DoGSD a useful resource for in-depth analysis in dog-/wolf-related studies.
资助信息973 program [2013CB835200 and 2013CB835202 to G.D.W.]; The Strategic Priority Research Program of the Chinese Academy of Sciences,Grant No.XDB13040500; Chinese Academy of Sciences [1731200000001 to W.Z.]; The Youth Innovation Promotion Association, Chinese Academy of Sciences [to G.D.W.]. Funding for open access charge: 973 program.
收录类别SCI
语种英语
WOS记录号WOS:000350210400113
公开日期2015-04-10
源URL[http://159.226.149.42:8088/handle/152453/8292]  
专题昆明动物研究所_分子进化基因组学
昆明动物研究所_遗传资源与进化国家重点实验室
作者单位1.Laboratory for Conservation and Utilization of Bioresource & Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming 650091, China
2.State Key Laboratory of Genetic Resources and Evolution, and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
3.Core Genomic Facility, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
4.Kunming College of Life Science, University of Chinese Academy of Sciences,Kunming 650204, China
5.CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China
6.Department of Molecular and Cell Biology, School of Life Sciences, University of Science and Technology of China, Hefei 230026, China
7.Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada
推荐引用方式
GB/T 7714
Bai B,Zhao WM,Tang BX,et al. DoGSD: the dog and wolf genome SNP database[J]. NUCLEIC ACIDS RESEARCH,2015,43(Database issue):D777-D783.
APA Bai B.,Zhao WM.,Tang BX.,Wang YQ.,Wang L.,...&Zhang YP[*].(2015).DoGSD: the dog and wolf genome SNP database.NUCLEIC ACIDS RESEARCH,43(Database issue),D777-D783.
MLA Bai B,et al."DoGSD: the dog and wolf genome SNP database".NUCLEIC ACIDS RESEARCH 43.Database issue(2015):D777-D783.

入库方式: OAI收割

来源:昆明动物研究所

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