Comparative genomic analysis reveals more functional nasal chemoreceptors in nocturnal mammals than in diurnal mammals
文献类型：期刊论文
| 作者 | Wang GD2; Zhu ZH1; Shi P[*]2; Zhang YP[*]1,2 |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2010 |
| 卷号 | 55期号:34页码:3901-3910 |
| 关键词 | nasal chemoreceptors adaptive evolution nocturnal mammal diurnal mammal morphological complexity |
| 通讯作者 | shipengsir@gmail.com ; zhangyp1@263.net.cn |
| 合作状况 | 其它 |
| 英文摘要 | Natural selection has a critical role in the diversity of morphological traits. However, the genetic basis underlying the evolution and diversity of morphological characteristics, particularly in the context an organism's behavior, lifestyle, and environment, is not well understood. The discovery of nasal chemoreceptors in mammals provided an opportunity to address this question. Here, we identify 4 nasal chemoreceptor gene families (V1R, V2R, OR, and TAAR) from horse, guinea pig, marmoset and orangutan genome sequences, respectively. Together with previously described mammalian nasal chemoreceptor gene repertoires, we found a significant positive correlation between functional gene number and morphological complexity, both in the main olfactory system and the vomeronasal system. The combined analysis of morphological data, behavioral data, and gene repertoires suggests that nocturnal mammals tend to possess more species-specific chemoreceptor genes and more complicated olfactory organs than diurnal mammals. Moreover, analysis of evolutionary forces revealed the existence of positive selection on the species-specific genes, likely reflecting the species-specific detection of odors and pheromones. Taken together, these results reflect a rare case of adaptation to circadian rhythm activity at the genome scale, and strongly suggest that the complexity of morphological olfactory organs and the diversification of nasal chemoreceptors in nocturnal mammals are under selection for the ability to perceive the variety of odors that nocturnal mammals may encounter in their particular dark environments. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the National Basic Research Program of China (2007CB411600), the Chinese Academy of Sciences (KSCX2-YW-N- 018) and Bureau of Science and Technology of Yunnan Province to Y-P. Zhang and by a start-up fund of the “Hundreds-Talent Program” from Chinese Academy of Sciences and Key Project from National Natural Science Foundation of China (30930015) to P. Shi. |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10440]  |
| 专题 | 昆明动物研究所_分子进化基因组学 昆明动物研究所_遗传资源与进化国家重点实验室 昆明动物研究所_进化与功能基因组学 |
| 作者单位 | 1.Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, Kunming 650223, China 2.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China |
| 推荐引用方式 GB/T 7714 | Wang GD,Zhu ZH,Shi P[*],et al. Comparative genomic analysis reveals more functional nasal chemoreceptors in nocturnal mammals than in diurnal mammals[J]. CHINESE SCIENCE BULLETIN,2010,55(34):3901-3910. |
| APA | Wang GD,Zhu ZH,Shi P[*],&Zhang YP[*].(2010).Comparative genomic analysis reveals more functional nasal chemoreceptors in nocturnal mammals than in diurnal mammals.CHINESE SCIENCE BULLETIN,55(34),3901-3910. |
| MLA | Wang GD,et al."Comparative genomic analysis reveals more functional nasal chemoreceptors in nocturnal mammals than in diurnal mammals".CHINESE SCIENCE BULLETIN 55.34(2010):3901-3910. |
入库方式： OAI收割
来源：昆明动物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。