Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities
文献类型:期刊论文
作者 | Wang JS1; Zheng YT2; Efferth T3; Wang RR2; Shen YM1; Hao XJ[*]1 |
刊名 | PHYTOCHEMISTRY
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出版日期 | 2005 |
卷号 | 66期号:6页码:697-701 |
关键词 | Glycosmis montana rutaceae diprenylated indole carbozole anti-HIV C8166 cytotoxicity leukaemia |
ISSN号 | 0031-9422 |
通讯作者 | haoxj@mail.kib.ac.cn |
合作状况 | 其它 |
英文摘要 | A diprenylated indole, (E)-3-(3-hydroxymethyl-2-butenyl)-7-(3-methyl-2-butenyl)-1H-indole (1), and six known carbazole alkaloids were isolated from the twigs and leaves of Glycosmis montana Pierre (Rutaceae). Their structures were determined on the basis of analysis of spectral evidence including 1D and 2D NMR and MS. The alkaloids (1-3) exhibited weak to moderate take in vitro inhibitory activity against HIV replication in C8166 cells, and they (as well as carbalexine A and B) had cytotoxic activity against the human leukaemia cell line CCRF-CEM. |
收录类别 | SCI |
资助信息 | The work was supported by grants from the Key Technologies R&D programme of Yunnan (2004NG12); CAS Knowledge Innovation Projects (KSCX2-SW-216), and National 863 Program (2003AA219142). |
原文出处 | 200566697.pdf |
语种 | 英语 |
公开日期 | 2010-08-24 |
源URL | [http://159.226.149.42:8088/handle/152453/4547] ![]() |
专题 | 昆明动物研究所_分子免疫药理学 |
作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Heilongton, Kunming, Yunnan 650204, PR China 2.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, PR China 3.German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany |
推荐引用方式 GB/T 7714 | Wang JS,Zheng YT,Efferth T,et al. Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities[J]. PHYTOCHEMISTRY,2005,66(6):697-701. |
APA | Wang JS,Zheng YT,Efferth T,Wang RR,Shen YM,&Hao XJ[*].(2005).Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities.PHYTOCHEMISTRY,66(6),697-701. |
MLA | Wang JS,et al."Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities".PHYTOCHEMISTRY 66.6(2005):697-701. |
入库方式: OAI收割
来源:昆明动物研究所
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