Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities
文献类型：期刊论文
| 作者 | Xiao WL1; Yang LM2; Gong NB3; Wu L3; Wang RR2; Pu JX1,4; Li XL1,4; Huang SX1,4; Zheng YT2; Li RT1 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2006 |
| 卷号 | 8期号:5页码:991-994 |
| ISSN号 | 1523-7060 |
| 通讯作者 | hdsun@mail.kib.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Rubriflordilactones A (1) and B (2), two novel highly unsaturated rearranged bisnortriterpenoids possessing a biosynthetically modified aromatic D-ring, were isolated from the leaves and stems of Schisandra rubriflora. Their structures were established on the basis of extensive spectroscopic methods, including two-dimensional NMR techniques, and confirmed by X-ray crystallographic analysis. Compound 1 showed weak anti-HIV-1 activity, and compound 2 exhibited an EC50 value of 9.75 mu g/mL (SI = 12.39) against HIV-1 replication with low cytotoxicity. |
| 收录类别 | SCI |
| 资助信息 | This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12). |
| 原文出处 | 20068991.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4571]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan 2.Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan 3.Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, P. R. Chin 4.Graduate School of the Chinese Academy of Sciences, Beijing 100039, P. R. China |
| 推荐引用方式 GB/T 7714 | Xiao WL,Yang LM,Gong NB,et al. Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities[J]. ORGANIC LETTERS,2006,8(5):991-994. |
| APA | Xiao WL.,Yang LM.,Gong NB.,Wu L.,Wang RR.,...&Sun HD[*].(2006).Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities.ORGANIC LETTERS,8(5),991-994. |
| MLA | Xiao WL,et al."Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities".ORGANIC LETTERS 8.5(2006):991-994. |
入库方式： OAI收割
来源：昆明动物研究所
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