Sphenalactones A-D, a new class of highly oxygenated trinortriterpenoids from Schisandra sphenanthera
文献类型：期刊论文
| 作者 | Xiao WL1; Yang LM2; Li LM1; Pu JX1; Huang SX1; Weng ZY1; Lei C1; Liu JP1; Wang RR2; Zheng YT2 |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2007 |
| 卷号 | 48期号:31页码:5543-5546 |
| 关键词 | Schisandra sphenanthera sphenalactones A-D trinortriterpenoid anti-HIV activity |
| ISSN号 | 0040-4039 |
| 通讯作者 | hdsun@mail.kib.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Four novel highly oxygenated trinortriterpenoids, sphenalactones A-D (1-4), were isolated from the leaves and stems of Schisandra sphenanthera and their structures were elucidated by extensive analysis of 1D and 2D NMR data. Compounds 1-4 featured a C-27 backbone and showed anti-HIV-1 activity with EC50 values in the range of 35.5-89.1 mu g/mL with low cytotoxicity against C8166 cells (CC50 > 200 mu g/mL). |
| 收录类别 | SCI |
| 资助信息 | This work was supported by grants from the Yong Aca- demic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological projects of China (2004BA719A14), the National Natural Sci- ence Foundation of China (No. 20402016) and project of Chinese Academy of Sciences (KSCX1-YW-R-24 and XiBuZhiGuang to W.-L., Xiao). |
| 原文出处 | 2007485543.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4587]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204 Yunnan, PR China 2.Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223 Yunnan, PR China |
| 推荐引用方式 GB/T 7714 | Xiao WL,Yang LM,Li LM,et al. Sphenalactones A-D, a new class of highly oxygenated trinortriterpenoids from Schisandra sphenanthera[J]. TETRAHEDRON LETTERS,2007,48(31):5543-5546. |
| APA | Xiao WL.,Yang LM.,Li LM.,Pu JX.,Huang SX.,...&Sun HD[*].(2007).Sphenalactones A-D, a new class of highly oxygenated trinortriterpenoids from Schisandra sphenanthera.TETRAHEDRON LETTERS,48(31),5543-5546. |
| MLA | Xiao WL,et al."Sphenalactones A-D, a new class of highly oxygenated trinortriterpenoids from Schisandra sphenanthera".TETRAHEDRON LETTERS 48.31(2007):5543-5546. |
入库方式： OAI收割
来源：昆明动物研究所
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