Three new compounds from Kadsura longipedunculata
文献类型：期刊论文
| 作者 | Pu JX1; Gao XM1; Lei C1; Xiao WL1; Wang RR2; Yang LB1; Zhao Y1; Li LM1; Huang SX1; Zheng YT2 |
| 刊名 | CHEMICAL & PHARMACEUTICAL BULLETIN
 |
| 出版日期 | 2008 |
| 卷号 | 56期号:8页码:1143-1146 |
| 关键词 | Kadsura longipedunculata lignan sesquiterpenoid anti-human immunodeficiency virus activity |
| ISSN号 | 0009-2363 |
| 通讯作者 | hdsun@mail.kib.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Two new tetrahydrofuran lignans, kadlongirins A and B (1, 2), a new cadinane-type sesquiterpenoid, 2,7-dihydroxy-1 1,1 2-dehydrocalamenene (3), together with seven known lignans, grandisin, fragransin B-1, vladirol F, kadsuralignan C, otobaphenol, isoanwulignan, and 4-[4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol, were isolated from the leaves and stems of Kadsura longipedunculata. The structures of these new compounds were elucidated by spectroscopic methods. Compound 2 exhibited weak anti-human immunodeficiency virus-1 activity with an EC50 value of 16.0 mu g/ml, and therapeutic index (TI) value of 6.7. |
| 收录类别 | SCI |
| 资助信息 | We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M). |
| 原文出处 | 2008561143.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4625]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences; Kunming 650204, P. R. China 2.Laboratory of Molecular Immunopharmacology, Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences; Kunming 650223, Yunnan, P. R. China |
| 推荐引用方式 GB/T 7714 | Pu JX,Gao XM,Lei C,et al. Three new compounds from Kadsura longipedunculata[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2008,56(8):1143-1146. |
| APA | Pu JX.,Gao XM.,Lei C.,Xiao WL.,Wang RR.,...&Sun HD[*].(2008).Three new compounds from Kadsura longipedunculata.CHEMICAL & PHARMACEUTICAL BULLETIN,56(8),1143-1146. |
| MLA | Pu JX,et al."Three new compounds from Kadsura longipedunculata".CHEMICAL & PHARMACEUTICAL BULLETIN 56.8(2008):1143-1146. |
入库方式： OAI收割
来源：昆明动物研究所
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