Octanorcucurbitane and cucurbitane triterpenoids from the tubers of Hemsleya endecaphylla with HIV-1 inhibitory activity
文献类型：期刊论文
| 作者 | Chen JC1; Zhang GH2; Zhang ZQ1; Qiu MH[*]1; Zheng YT2; Yang LM2; Yu KB3 |
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2008 |
| 卷号 | 71期号:1页码:153-155 |
| ISSN号 | 0163-3864 |
| 通讯作者 | mhchiu@mail.kib.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Two new cucurbitacins, endecaphyllacins A (1) and B (2), together with six known analogues (3-8), were isolated from the tubers of Hemsleya endecaphylla. The structures of 1 and 2 were elucidated by NMR and MS spectroscopic analysis. The relative stereochemistry of I was determined by single-crystal X-ray diffraction. Compound 4 (cucurbitacin B) showed potent anti-HIV-1 in C8166 cells (EC = 0.09 mu g/mL) with a selectivity index of 16.7. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by grants from the National Natural Science Foundation of China (Grant No. 39970086) and the Chinese Academy of Sciences (XiBuZhiGuang Project) for financial support. |
| 原文出处 | 200871153.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/4651]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, People’s Republic of China 2.Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, People’s Republic of China 3.Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, Sichuan, People’s Republic of China |
| 推荐引用方式 GB/T 7714 | Chen JC,Zhang GH,Zhang ZQ,et al. Octanorcucurbitane and cucurbitane triterpenoids from the tubers of Hemsleya endecaphylla with HIV-1 inhibitory activity[J]. JOURNAL OF NATURAL PRODUCTS,2008,71(1):153-155. |
| APA | Chen JC.,Zhang GH.,Zhang ZQ.,Qiu MH[*].,Zheng YT.,...&Yu KB.(2008).Octanorcucurbitane and cucurbitane triterpenoids from the tubers of Hemsleya endecaphylla with HIV-1 inhibitory activity.JOURNAL OF NATURAL PRODUCTS,71(1),153-155. |
| MLA | Chen JC,et al."Octanorcucurbitane and cucurbitane triterpenoids from the tubers of Hemsleya endecaphylla with HIV-1 inhibitory activity".JOURNAL OF NATURAL PRODUCTS 71.1(2008):153-155. |
入库方式： OAI收割
来源：昆明动物研究所
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