Molecular epidemiology of the heterosexual HIV-1 transmission in Kunming, Yunnan Province of China suggests origin from the local IDU epidemic
文献类型：期刊论文
| 作者 | Li XJ1,2; Kusagawa S1; Xia XS3; Yang CJ1,4; Wang QQ1,2; Yokota Y1; Hoshina Y1; Onogi T1; Nohtomi K1; Imamura Y1 |
| 刊名 | AIDS RESEARCH AND HUMAN RETROVIRUSES
 |
| 出版日期 | 2005 |
| 卷号 | 21期号:11页码:977-980 |
| ISSN号 | 0889-2229 |
| 通讯作者 | takebe@nih.go.jp |
| 合作状况 | 其它 |
| 英文摘要 | Molecular epidemiological investigation was conducted among injecting drug users (IDUs) (n = 11) and heterosexuals (n = 15) in Kunming, Yunnan Province of China. HIV-1 genotypes were determined based on the nucleotide sequences of 2.6-kb gag-RT region. The distribution of genotypes among IDUs was as follows: CRF07_BC (5/11) and CRF08_BC (5/11); subtype B' (1/11). Similarly, a majority of Kunming heterosexuals (14/15) were infected with CRF07_BC (4/15), CRF08_BC (6/15), or subtype B' (4/15), known to predominate among IDUs in China. This contrasts with trends in the coastal regions of China and surrounding southeastern Asian countries, where CRF01_AE predominates among heterosexuals. The heterosexual HIV-1 epidemic in Kunming thus appears to derive from the local IDU epidemic. Of note, subtype B' was the most prevalent strain among heterosexuals before 1997, while CRF07_BC and CRF08_BC became predominant in 2002, indicating a transition of HIV-1 genotype distribution between the early and the more recent samples from Kunming heterosexuals. |
| 收录类别 | SCI |
| 资助信息 | This study was supported by grants from the Ministry of Health, Labour and Welfare, Ministry of Education, Science and Technology, and Japanese Foundation for AIDS Prevention (JFAP). X.-J. L. is a recipient of a Re- search Resident Fellowship from JFAP. C.Y. is a research fel- low of the Japan–China Medical Association. Q.W. is a Fellow of the Takeda Science Foundation. |
| 原文出处 | 200521977.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/5353]  |
| 专题 | 昆明动物研究所_其他 |
| 作者单位 | 1.Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan. 2.Institute of Dermatology, Chinese Academy of Medical Sciences, 12 Jiangwangmiao Road, Nanjing 210042, The People’s Republic of China 3.Kunming University of Science and Technology, Kunming, Yunnan 650224, The People’s Republic of China 4.Yunnan Provincial Health and Anti-epidemic Center, 158 Dongsi Road, Kunming 650022, The People’s Republic of China 5.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, The People’s Republic of China 6.Kunming Chinaware Biotechnology, Yunnan 650106, The People’s Republic of China |
| 推荐引用方式 GB/T 7714 | Li XJ,Kusagawa S,Xia XS,et al. Molecular epidemiology of the heterosexual HIV-1 transmission in Kunming, Yunnan Province of China suggests origin from the local IDU epidemic[J]. AIDS RESEARCH AND HUMAN RETROVIRUSES,2005,21(11):977-980. |
| APA | Li XJ.,Kusagawa S.,Xia XS.,Yang CJ.,Wang QQ.,...&Takebe Y[*].(2005).Molecular epidemiology of the heterosexual HIV-1 transmission in Kunming, Yunnan Province of China suggests origin from the local IDU epidemic.AIDS RESEARCH AND HUMAN RETROVIRUSES,21(11),977-980. |
| MLA | Li XJ,et al."Molecular epidemiology of the heterosexual HIV-1 transmission in Kunming, Yunnan Province of China suggests origin from the local IDU epidemic".AIDS RESEARCH AND HUMAN RETROVIRUSES 21.11(2005):977-980. |
入库方式： OAI收割
来源：昆明动物研究所
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