Cycloartane Triterpenoids from Cassia occidentalis
文献类型：期刊论文
| 作者 | Li SF1,2; Di YT1; Luo RH3; Zheng YT3; Wang YH1; Fang X1; Zhang Y1; Li L4; He HP1; Li SL[*]1 |
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2012 |
| 卷号 | 78期号:8页码:821-827 |
| 关键词 | Cassia occidentalis Leguminosae cycloartane triterpenoids cycloccidentalic acids A and B cycloccidentalisides I-V |
| 通讯作者 | lisl@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
| 中文摘要 | A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds were elucidated through detailed spectroscopic analyses, including 1D and 2D NMR techniques, and chemical methods. Compounds 2 and 5 showed modest anti-HIV-1 activities with EC50 values of 2.23 mu M and 4.36 mu M, respectively, in comparison to the positive control. |
| 英文摘要 | A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds were elucidated through detailed spectroscopic analyses, including 1D and 2D NMR techniques, and chemical methods. Compounds 2 and 5 showed modest anti-HIV-1 activities with EC50 values of 2.23 mu M and 4.36 mu M, respectively, in comparison to the positive control. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000304449300013 |
| 公开日期 | 2012-09-17 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7110]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, P. R. China 2.Graduate University of Chinese Academy of Sciences, Beijing, P. R. China 3.Key Laboratory of Animal Models and Human Diseases Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, P. R. Chin 4.Yunnan Pharmacological Laboratories of Natural Products, Kunming Medical College, Kunming, Yunnan, P. R. China |
| 推荐引用方式 GB/T 7714 | Li SF,Di YT,Luo RH,et al. Cycloartane Triterpenoids from Cassia occidentalis[J]. PLANTA MEDICA,2012,78(8):821-827. |
| APA | Li SF.,Di YT.,Luo RH.,Zheng YT.,Wang YH.,...&Hao XJ[*].(2012).Cycloartane Triterpenoids from Cassia occidentalis.PLANTA MEDICA,78(8),821-827. |
| MLA | Li SF,et al."Cycloartane Triterpenoids from Cassia occidentalis".PLANTA MEDICA 78.8(2012):821-827. |
入库方式： OAI收割
来源：昆明动物研究所
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