Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea
文献类型：期刊论文
| 作者 | Liang CQ1,3,4; Shi YM1,3; Luo RH2,3; Li XY1,3; Gao ZH1,3; Li XN1; Yang LM2; Shang SZ1,3; Li Y1; Zheng YT2 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2012 |
| 卷号 | 14期号:24页码:6362-6365 |
| 通讯作者 | xwl@mail.kib.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | A pair of new triterpenoid epimers, kadcoccitones A (1) and B (2), together with a new biogenetically related compound kadcoccitone C (3), were isolated from Kadsura coccinea. The epimers featured an unprecedented carbon skeleton with a 6/6/5/5-fused tetracyclic ring system unit and a C-9 side chain. Their structures were determined by spectroscopic data, ECD calculation, and single-crystal X-ray diffraction. Compounds 1 and 3 showed anti-HIV-1 activity with an EC50 value of 47.91 and 32.66 mu g/mL, respectively. |
| 收录类别 | SCI |
| 资助信息 | This pro- ject was supported financially by the NSFC (20802082, 30830115, 81102483), the CAS grants (KSCX2-EW-Q-10, KSCX1-YW-R-24), the 973 programs (2009CB522300, 2009CB940900), the Natural Science Foundation of Yunnan Province (2012FB178), the project of recruited top talent of sciences and technology of Yunnan Province (2009C1120), and the Key Scientific and Technological ProjectsofChina(2009ZX09501-029,2012ZX10001-006). |
| 语种 | 英语 |
| WOS记录号 | WOS:000312564500062 |
| 公开日期 | 2013-09-18 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7650]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, P. R. China 2.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academyof Sciences & YunnanProvince, Kunming Institute of Zoology, Chinese Academyof Sciences, Kunming 650223, Yunnan, P. R. China 3.University of Chinese Academy of Sciences, Beijing100049,P.R.China 4.Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, Yunnan, P. R. China |
| 推荐引用方式 GB/T 7714 | Liang CQ,Shi YM,Luo RH,et al. Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea[J]. ORGANIC LETTERS,2012,14(24):6362-6365. |
| APA | Liang CQ.,Shi YM.,Luo RH.,Li XY.,Gao ZH.,...&Sun HD[*].(2012).Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea.ORGANIC LETTERS,14(24),6362-6365. |
| MLA | Liang CQ,et al."Kadcoccitones A and B, Two New 6/6/5/5-Fused Tetracyclic Triterpenoids from Kadsura coccinea".ORGANIC LETTERS 14.24(2012):6362-6365. |
入库方式： OAI收割
来源：昆明动物研究所
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