New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities
文献类型：期刊论文
| 作者 | Shi YM1,3; Zhong WM1,3; Chen H2; Wang RR2; Shang SZ1,3; Liang CQ1,3; Gao ZH1,3; Zheng YT2; Xiao WL[*]1; Sun HD[*]1 |
| 刊名 | CHINESE JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2014 |
| 卷号 | 32期号:8页码:734-740 |
| 关键词 | Schisandraceae Schisandra chinensis lignan anti-HIV-1 |
| 通讯作者 | xwl@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Six new lignans (1-6), as well as five known ones (7-11) were isolated from the leaves and stems of Schisandra chinensis. The structures of 1-6 were established on the basis of spectroscopic methods including 1D-and 2D-NMR techniques and CD experiments. Compound 1 was the first example of naturally occurring N-containing lignans featuring a nicotinoyl group. All the new compounds were evaluated for their anti-HIV-1 activities and showed EC50 values in the range 17.89-138.23 mu g/mL. |
| 收录类别 | SCI |
| 资助信息 | This project was supported financially by the Na- tional Natural Science Foundation of China (Nos. 81373290, 81102483), the Natural Science Foundation of Yunnan Province (No. 2012FB178), and the Chinese Academy of Sciences grant (No. KSCX2-EW-Q-10) and sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry to W.-L. Xiao. |
| 语种 | 英语 |
| WOS记录号 | WOS:000341236900015 |
| 公开日期 | 2014-10-10 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8024]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China 2.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China 3.University of Chinese Academy of Sciences, Beijing 100049, China |
| 推荐引用方式 GB/T 7714 | Shi YM,Zhong WM,Chen H,et al. New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities[J]. CHINESE JOURNAL OF CHEMISTRY,2014,32(8):734-740. |
| APA | Shi YM.,Zhong WM.,Chen H.,Wang RR.,Shang SZ.,...&Sun HD[*].(2014).New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities.CHINESE JOURNAL OF CHEMISTRY,32(8),734-740. |
| MLA | Shi YM,et al."New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities".CHINESE JOURNAL OF CHEMISTRY 32.8(2014):734-740. |
入库方式： OAI收割
来源：昆明动物研究所
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