Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr
文献类型：期刊论文
| 作者 | Huang SZ1,2; Zhang X3; Ma QY1; Peng H2; Zheng YT3; Hu JM2; Dai HF1; Zhou J[*]2; Zhao YX[*]1 |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2014 |
| 卷号 | 95期号:X页码:34-41 |
| 关键词 | Anti-HIV-1 Chemotaxonomy Excoecaria acerifolia Euphorbiaceae Excoecafolin |
| 通讯作者 | junzhou3264@126.com ; zhaoyx1011@163.com |
| 合作状况 | 其它 |
| 英文摘要 | Three tigliane-type diterpenoids named excoecafolins A-C and two daphnane-type diterpenoids named excoecafolins D and E, together with 13 known compounds, were isolated from the EtOAc extract of Excoecaria acerzfolia Didr. Their structures were elucidated through the analysis of the spectroscopic data. The anti-HIV-1 activity evaluation of five of these compounds showed that four possessed moderate anti-HIV-1 activities with EC50 0.258, 0.036, 0.046, and 0.978 mu M, SI >1,836.9,431.1, 298.7, and >503.7, respectively. Additionally, the chemotaxonomic issue of the affinity correlation between Thymelaeceae and Euphorbiaceae is discussed based on the isolates. |
| 收录类别 | SCI |
| 资助信息 | This work was financially supported by the National Natural Science Foundation of China (31300294), the Special Fund for Agro-scientific Research in the Public Interest (201303117), the National Support Science and Technology Subject (2013BAI11B04), and the Major Technology Project of Hainan (ZDZX2013008-4, ZDZX2013023-1). |
| 语种 | 英语 |
| WOS记录号 | WOS:000336819400005 |
| 公开日期 | 2014-10-15 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8042]  |
| 专题 | 昆明动物研究所_分子免疫药理学 |
| 作者单位 | 1.Key Laboratory of Biology and Genetic Resources of Tropical Crops, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China 2.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China 3.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650204, PR China |
| 推荐引用方式 GB/T 7714 | Huang SZ,Zhang X,Ma QY,et al. Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr[J]. FITOTERAPIA,2014,95(X):34-41. |
| APA | Huang SZ.,Zhang X.,Ma QY.,Peng H.,Zheng YT.,...&Zhao YX[*].(2014).Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr.FITOTERAPIA,95(X),34-41. |
| MLA | Huang SZ,et al."Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr".FITOTERAPIA 95.X(2014):34-41. |
入库方式： OAI收割
来源：昆明动物研究所
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