Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum
文献类型：期刊论文
| 作者 | Cheng YY1,2; Chen H2,3; He HP1; Zhang Y1; Li SF1,2; Tang GH1,2; Guo LL1; Yang W1,2; Zhu F1,2; Zheng YT[*]3 |
| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2013 |
| 卷号 | 96期号:X页码:360-369 |
| 关键词 | Trigothysoids A-P Anti-HIV-1 Trigonostemon thyrsoideum Euphorbiaceae Daphnane diterpenoids |
| 通讯作者 | zhengyt@mail.kiz.ac.cn ; lisl@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
| 英文摘要 | Sixteen daphnane diterpenoids, trigothysoids A-P, along with 15 known ones, were isolated from the methanol extract of the twigs and leaves of Trigonostemon thy rsoideum. Their structures were established by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry. The anti-HIV-1 activity of the compounds was also evaluated in vitro, and five compounds demonstrated potent anti-HIV-1 activity, with EC50 values of 0.015-0.001 nM and TI values of 1618-17,619. |
| 收录类别 | SCI |
| 资助信息 | This work was supported financially by the Ministry of Science and Technology of China (2009CB522300 and 2009CB940900), the National Natural Science Funding of China (21072199), the Natural Science Funding of Yunnan Province (2009CD112), and the Foun- dation of Chinese Academy of Sciences to H.P. He. |
| 语种 | 英语 |
| WOS记录号 | WOS:000328869500038 |
| 公开日期 | 2014-10-16 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8070]  |
| 专题 | 昆明动物研究所_分子免疫药理学 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People’s Republic of China 2.Graduate University of Chinese Academy of Sciences, Beijing 100039, People’s Republic of China 3.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, People’s Republic of China |
| 推荐引用方式 GB/T 7714 | Cheng YY,Chen H,He HP,et al. Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum[J]. PHYTOCHEMISTRY,2013,96(X):360-369. |
| APA | Cheng YY.,Chen H.,He HP.,Zhang Y.,Li SF.,...&Hao XJ[*].(2013).Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum.PHYTOCHEMISTRY,96(X),360-369. |
| MLA | Cheng YY,et al."Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum".PHYTOCHEMISTRY 96.X(2013):360-369. |
入库方式： OAI收割
来源：昆明动物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。