Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity
文献类型：期刊论文
| 作者 | Li SF1,2; Zhang Y1; Huang N2,3; Zheng YT3; Di YT1; Li SL1; Cheng YY1,2; He HP[*]1; Hao XJ[*]1 |
| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2013 |
| 卷号 | 93期号:X页码:216-221 |
| 通讯作者 | hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | Thirteen highly oxygenated daphnane diterpenoids, including six known compounds, were isolated from the stems of Trigonostemon lii. The structures were elucidated by extensive spectroscopic analyses including 2D NMR spectroscopy (HSQC, H-1-H-1 COSY, HMBC, and ROESY) and mass spectrometry. The absolute stereochemistries of compounds were established on the basis of CD spectra. Four of the compounds showed modest anti-HIV-1 activity (EC50 = 2.04, 9.17, 11.42, and 9.05 mu g/ml, TI = 26.49, >21.81, 9.32, and 9.56, respectively) in vitro. |
| 收录类别 | SCI |
| 资助信息 | This work was supported financially by the Ministry of Science and Technology of China (2009CB522300 and 2009CB940900), National Natural Science Funding of China (21072199), Natural Science Funding of Yunnan Province (2009CD112), Foundation of Chinese Academy of Sciences to H.P. He, and the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2010CI047). |
| 语种 | 英语 |
| WOS记录号 | WOS:000323630000025 |
| 公开日期 | 2014-10-17 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8083]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People’s Republic of China 2.Graduate University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China 3.Key Laboratory of Animal Models and Human Diseases Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, People’s Republic of China |
| 推荐引用方式 GB/T 7714 | Li SF,Zhang Y,Huang N,et al. Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity[J]. PHYTOCHEMISTRY,2013,93(X):216-221. |
| APA | Li SF.,Zhang Y.,Huang N.,Zheng YT.,Di YT.,...&Hao XJ[*].(2013).Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity.PHYTOCHEMISTRY,93(X),216-221. |
| MLA | Li SF,et al."Daphnane diterpenoids from the stems of Trigonostemon lii and their anti-HIV-1 activity".PHYTOCHEMISTRY 93.X(2013):216-221. |
入库方式： OAI收割
来源：昆明动物研究所
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