中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 昆明动物研究所
  3. 昆明动物研究所
  4. 动物模型与人类重大疾病机理重点实验室
  5. 分子免疫药理学
Bioactive Lignans from the Leaves and Stems of Schisandra wilsoniana

文献类型：期刊论文

作者Yang GY1,3; Wang RR2; Gao ZH1; Li YK1,4; Yang LM2; Li XN1; Shang SZ1; Zheng YT2; Xiao WL[*]1; Sun HD[*]1
刊名NATURAL PRODUCT COMMUNICATIONS
出版日期2013
卷号8期号:4页码:467-470
关键词Schisandra wilsoniana Lignans Anti-HIV-1 activities Antitumor activities
通讯作者xwl@mail.kib.ac.cn ; hdsun@mail.kib.ac.cn
合作状况其它
英文摘要Three new dibenzocyclooctadiene lignans, marlignans M-O (1-3), together two known ones, were isolated from the leaves and stems of Schisandra wilsoniana. The structures of 1-3 were elucidated by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. Compound 2 showed anti-HIV-1 activity with an EC50 value of 5.82 mu g/mL and a therapeutic index (TI) of more than 12.8. Compound 3 showed obvious bioactivity in inhibiting Epstein-Barr virus early antigen (EBV-EA) activation.
收录类别SCI
资助信息This project was supported financially by the CAS grants (KSCX2-EW-Q-10 and KSCX1-YW-R-24), the Natural Science Foundation of Yunnan Province (2012FB178), the NSFC (20802082 and 30830115), the 973 programs (2009CB522300 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Key Scientific and Technological Projects of China (2009ZX09501-029).
语种英语
WOS记录号WOS:000317810000014
公开日期2014-10-20
源URL[http://159.226.149.42:8088/handle/152453/8106]  
专题昆明动物研究所_分子免疫药理学
昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, P. R. China
2.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, P. R.China
3.Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science, Kunming 650106, Yunnan, P. R. China
4.School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, Yunnan, P. R. China
推荐引用方式
GB/T 7714		 Yang GY,Wang RR,Gao ZH,et al. Bioactive Lignans from the Leaves and Stems of Schisandra wilsoniana[J]. NATURAL PRODUCT COMMUNICATIONS,2013,8(4):467-470.
APA Yang GY.,Wang RR.,Gao ZH.,Li YK.,Yang LM.,...&Sun HD[*].(2013).Bioactive Lignans from the Leaves and Stems of Schisandra wilsoniana.NATURAL PRODUCT COMMUNICATIONS,8(4),467-470.
MLA Yang GY,et al."Bioactive Lignans from the Leaves and Stems of Schisandra wilsoniana".NATURAL PRODUCT COMMUNICATIONS 8.4(2013):467-470.

入库方式： OAI收割

来源：昆明动物研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。