Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia
文献类型：期刊论文
| 作者 | Huang SZ1,4; Zhang X3; Ma QY1,4; Zheng YT3; Xu FQ2; Peng H2; Dai HF1,4; Zhou J[*]2; Zhao YX[*]1,4 |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2013 |
| 卷号 | 91期号:X页码:224-230 |
| 关键词 | Excoecaria acerifolia Euphorbiaceae Anti-HIV Diterpenoid Triterpenoid |
| 通讯作者 | junzhou3264@126.com ; zhaoyouxing@itbb.org.cn |
| 合作状况 | 其它 |
| 英文摘要 | Five new diterpenoids named excocarinols A-E (1-5) including three pimaranes, one cleistanthane, and one nor-beyerane, together with nine known compounds, were isolated from the EtOAc extract of the Chinese ethnodrug Gua-jing-ban (Excoecaria acerifolia Didr.). Their structures were elucidated by the analysis of spectroscopic data including 1D, 2D NMR and HR-MS. The anti-HIV-1 bioassay on the diterpenoids showed that excocarinol A (1) exhibited moderate anti-HIV-1 activity with EC50 5.58 mu M and SI (Selection Index) over 112.71. |
| 收录类别 | SCI |
| 资助信息 | This work wasfinancially supported by the Special Fund for Agro-scientific Research in the Public Interest (201303117), the National Support Science and Technology Subject (2013BAI11B04), and the Fundamental Scientific Research Funds for CATAS (1630052013001; ITBB110301). |
| 语种 | 英语 |
| WOS记录号 | WOS:000327574300033 |
| 公开日期 | 2014-10-22 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8124]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, People's Republic of China 2.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China 3.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Science & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, People's Republic of China 4.Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Haikou 571101, People's Republic of China |
| 推荐引用方式 GB/T 7714 | Huang SZ,Zhang X,Ma QY,et al. Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia[J]. FITOTERAPIA,2013,91(X):224-230. |
| APA | Huang SZ.,Zhang X.,Ma QY.,Zheng YT.,Xu FQ.,...&Zhao YX[*].(2013).Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia.FITOTERAPIA,91(X),224-230. |
| MLA | Huang SZ,et al."Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia".FITOTERAPIA 91.X(2013):224-230. |
入库方式： OAI收割
来源：昆明动物研究所
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