Analysis of immunoglobulin, complements and CRP levels in serum of captive northern pig-tailed macaques (Macaca leonina)
文献类型：期刊论文
| 作者 | Zhang XL1,2; Pang W2; Zheng YT[*]2,4; Deng DY3; Lv LB4; Feng Y1 |
| 刊名 | Zoological Research
 |
| 出版日期 | 2014 |
| 卷号 | 35期号:3页码:196−203 |
| 关键词 | Northern pig-tailed macaque (Macaca leonina) C-reactive Immunoglobulin Complement |
| 通讯作者 | Zhangyt@mail.kiz.ac.cn |
| 合作状况 | 其它 |
| 英文摘要 | The northern pig-tailed macaque (NPM，Macaca leonina) has become a widely used animal model in biomedical research. In this study, we measured serum immunoglobulin IgG, IgM, IgA, complement C3, C4 and CRP levels in 3-11 year old captive northern pig-tailed macaques using HITACHI 7600-20 automated chemistry analyzer in order to determine the influences of age and gender on these items. The results showed that serum IgA, IgM, C3 and C4 levels were not correlated with age (P>0.05), while serum IgG levels increased progressively with age (r=0.202;P=0.045). Serum IgG, IgA, IgM and C3 levels were higher in females than in males (P<0.05). Moreover, serum C3 concentration was both positively and strongly correlated with that of C4 (r=0.700; P<0.0001). This study provides basic serum immunoglobulin and complement data of captive northern pig-tailed macaques, which may prove useful for future breeding efforts and biomedical research. |
| 收录类别 | 其他 |
| 资助信息 | This work was supported by the National Natural Science Foundation of China (81172876, U0832601, 81273251, U1202228); the National Special Science Research Program of China (2012CBA01305); the National Science and Technology Major Project (2013ZX10001-002, 2012ZX10001-007) and the Knowledge Innovation Program of CAS (KSCX2-EW-R-13). |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/9288]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 昆明动物研究所_中国科学院昆明灵长类研究中心 |
| 作者单位 | 1.Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan 650500, China 2.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China 3.Department of Clinical Laboratory, the Second Hospital of Yunnan Province, Kunming, Yunnan 650021, China 4.Kunming Primate Research Center, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China |
| 推荐引用方式 GB/T 7714 | Zhang XL,Pang W,Zheng YT[*],et al. Analysis of immunoglobulin, complements and CRP levels in serum of captive northern pig-tailed macaques (Macaca leonina)[J]. Zoological Research,2014,35(3):196−203. |
| APA | Zhang XL,Pang W,Zheng YT[*],Deng DY,Lv LB,&Feng Y.(2014).Analysis of immunoglobulin, complements and CRP levels in serum of captive northern pig-tailed macaques (Macaca leonina).Zoological Research,35(3),196−203. |
| MLA | Zhang XL,et al."Analysis of immunoglobulin, complements and CRP levels in serum of captive northern pig-tailed macaques (Macaca leonina)".Zoological Research 35.3(2014):196−203. |
入库方式： OAI收割
来源：昆明动物研究所
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