Synthesis and Biological Evaluation of Andrographolide Derivatives as Potent Anti-HIV Agents*
文献类型：期刊论文
| 作者 | Wang B1; Li J2; Zheng YT3; Huang WL[*]1; Zhang HB1; Qian H[*]1 |
| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2011 |
| 卷号 | 22期号:7页码:781-784 |
| 关键词 | Andrographolide Anti-HIV Derivatives Natural products Synthesis |
| 通讯作者 | ydhuangwenlong@126.com ; qianhai24@163.com |
| 合作状况 | 其它 |
| 英文摘要 | A series of Andro derivatives were described and evaluated for their anti-HIV activity in vitro. Compound 10 and 16b, of which Ti were > 10, had some anti-HIV-1 activity in vitro. Therein, compound 10 which was the best potent compound, could serve as a new lead for further development of anti-AIDS agents. (C) 2011 Wen Long Huang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. |
| 收录类别 | SCI |
| 资助信息 | Thework was supported by the National Natural ScienceFundation ofChina (No. 30772647)and the special major science and technology project of ‘‘Creation of Major New Drugs’’ (No. 2009ZX09102-033). |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10418]  |
| 专题 | 昆明动物研究所_分子免疫药理学 昆明动物研究所_动物模型与人类重大疾病机理重点实验室 |
| 作者单位 | 1.Center of Drug Discovery, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China 2.School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China 3.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China |
| 推荐引用方式 GB/T 7714 | Wang B,Li J,Zheng YT,et al. Synthesis and Biological Evaluation of Andrographolide Derivatives as Potent Anti-HIV Agents*[J]. CHINESE CHEMICAL LETTERS,2011,22(7):781-784. |
| APA | Wang B,Li J,Zheng YT,Huang WL[*],Zhang HB,&Qian H[*].(2011).Synthesis and Biological Evaluation of Andrographolide Derivatives as Potent Anti-HIV Agents*.CHINESE CHEMICAL LETTERS,22(7),781-784. |
| MLA | Wang B,et al."Synthesis and Biological Evaluation of Andrographolide Derivatives as Potent Anti-HIV Agents*".CHINESE CHEMICAL LETTERS 22.7(2011):781-784. |
入库方式： OAI收割
来源：昆明动物研究所
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