中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
More evidence for non-maternal inheritance of mitochondrial DNA?

文献类型:期刊论文

作者Bandelt HJ[*]1; Kong QP2; Parson W3; Salas A4
刊名JOURNAL OF MEDICAL GENETICS
出版日期2005
卷号42期号:12页码:957-960
ISSN号0022-2593
通讯作者bandelt@math.uni-hamburg.de
合作状况其它
英文摘要Background: A single case of paternal co-transmission ofmitochondrial DNA (mtDNA) in humans has been reported so far. Objective: To find potential instances of non-maternal inheritance of mtDNA. Methods: Published medical case studies (of single patients) were searched for irregular mtDNA patterns by comparing the given haplotype information for different clones or tissues with the worldwide mtDNA database as known to date-a method that has proved robust and reliable for the detection of flawed mtDNA sequence data. Results: More than 20 studies were found reporting clear cut instances with mtDNAs of different ancestries in single individuals. As examples, cases are reviewed from recent published reports which, at face value, may be taken as evidence for paternal inheritance of mtDNA or recombination. Conclusions: Multiple types (or recombinant types) of quite dissimilar mitochondrial DNA from different parts of the known mtDNA phylogeny are often reported in single individuals. From re-analyses and corrigenda of forensic mtDNA data, it is apparent that the phenomenon of mixed or mosaic mtDNA can be ascribed solely to contamination and sample mix up.
收录类别SCI
原文出处200542957.pdf
语种英语
公开日期2010-08-24
源URL[http://159.226.149.42:8088/handle/152453/4773]  
专题昆明动物研究所_分子人类学
昆明动物研究所_细胞与分子进化重点实验室
作者单位1.Fachbereich Mathematik, Universita ¨t Hamburg, Hamburg, Germany
2.Key Laboratory of Cellular and Molecular Evolution and Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
3.nstitute of Legal Medicine, Innsbruck Medical University, Innsbruck, Austria
4.Unidad de Gene ´tica, Instituto de Medicina Legal, Facultad de Medicina, Santiago de Compostela, Galicia, Spain
推荐引用方式
GB/T 7714
Bandelt HJ[*],Kong QP,Parson W,et al. More evidence for non-maternal inheritance of mitochondrial DNA?[J]. JOURNAL OF MEDICAL GENETICS,2005,42(12):957-960.
APA Bandelt HJ[*],Kong QP,Parson W,&Salas A.(2005).More evidence for non-maternal inheritance of mitochondrial DNA?.JOURNAL OF MEDICAL GENETICS,42(12),957-960.
MLA Bandelt HJ[*],et al."More evidence for non-maternal inheritance of mitochondrial DNA?".JOURNAL OF MEDICAL GENETICS 42.12(2005):957-960.

入库方式: OAI收割

来源:昆明动物研究所

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