More evidence for non-maternal inheritance of mitochondrial DNA?
文献类型:期刊论文
作者 | Bandelt HJ[*]1; Kong QP2; Parson W3; Salas A4 |
刊名 | JOURNAL OF MEDICAL GENETICS
![]() |
出版日期 | 2005 |
卷号 | 42期号:12页码:957-960 |
ISSN号 | 0022-2593 |
通讯作者 | bandelt@math.uni-hamburg.de |
合作状况 | 其它 |
英文摘要 | Background: A single case of paternal co-transmission ofmitochondrial DNA (mtDNA) in humans has been reported so far. Objective: To find potential instances of non-maternal inheritance of mtDNA. Methods: Published medical case studies (of single patients) were searched for irregular mtDNA patterns by comparing the given haplotype information for different clones or tissues with the worldwide mtDNA database as known to date-a method that has proved robust and reliable for the detection of flawed mtDNA sequence data. Results: More than 20 studies were found reporting clear cut instances with mtDNAs of different ancestries in single individuals. As examples, cases are reviewed from recent published reports which, at face value, may be taken as evidence for paternal inheritance of mtDNA or recombination. Conclusions: Multiple types (or recombinant types) of quite dissimilar mitochondrial DNA from different parts of the known mtDNA phylogeny are often reported in single individuals. From re-analyses and corrigenda of forensic mtDNA data, it is apparent that the phenomenon of mixed or mosaic mtDNA can be ascribed solely to contamination and sample mix up. |
收录类别 | SCI |
原文出处 | 200542957.pdf |
语种 | 英语 |
公开日期 | 2010-08-24 |
源URL | [http://159.226.149.42:8088/handle/152453/4773] ![]() |
专题 | 昆明动物研究所_分子人类学 昆明动物研究所_细胞与分子进化重点实验室 |
作者单位 | 1.Fachbereich Mathematik, Universita ¨t Hamburg, Hamburg, Germany 2.Key Laboratory of Cellular and Molecular Evolution and Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China 3.nstitute of Legal Medicine, Innsbruck Medical University, Innsbruck, Austria 4.Unidad de Gene ´tica, Instituto de Medicina Legal, Facultad de Medicina, Santiago de Compostela, Galicia, Spain |
推荐引用方式 GB/T 7714 | Bandelt HJ[*],Kong QP,Parson W,et al. More evidence for non-maternal inheritance of mitochondrial DNA?[J]. JOURNAL OF MEDICAL GENETICS,2005,42(12):957-960. |
APA | Bandelt HJ[*],Kong QP,Parson W,&Salas A.(2005).More evidence for non-maternal inheritance of mitochondrial DNA?.JOURNAL OF MEDICAL GENETICS,42(12),957-960. |
MLA | Bandelt HJ[*],et al."More evidence for non-maternal inheritance of mitochondrial DNA?".JOURNAL OF MEDICAL GENETICS 42.12(2005):957-960. |
入库方式: OAI收割
来源:昆明动物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。