Vitamin D status and its association with adiposity and oxidative stress in schoolchildren
文献类型：期刊论文
| 作者 | Zhang HQ1; Teng JH1,2; Li Y1; Li XX1; He YH1,3; He X1; Sun CH[*]1 |
| 刊名 | NUTRITION
 |
| 出版日期 | 2014 |
| 卷号 | 30期号:9页码:1040-1044 |
| 关键词 | Superoxide dismutase Schoolchildren Vitamin D deficiency Adiposity |
| 通讯作者 | Sun2002changhao@yahoo.com |
| 合作状况 | 其它 |
| 英文摘要 | Objective: The aim of this study was to evaluate serum 25-hydroxyvitamin D [25(OH)D] level and its association with adiposity, inflammation, and oxidative stress in schoolchildren. Methods: A total of 1488 schoolchildren ages 7 to 11 y were recruited in Harbin, China (latitude: 44 degrees 04'N-46 degrees 40'N) in May. Serum 25(OH)D, which is an indicator of vitamin D status, was determined. Anthropometric data were collected following general physical examinations. Serum lipids, glucose metabolism indices, inflammatory molecules, and oxidative stress markers were determined. Dietary intake and physical activity also were assessed. Results: The median serum 25(OH)D concentration was 18.4 ng/mL. Of the 1488 schoolchildren included, 839 (56.4%) had vitamin D deficiency [25(OH)D < 20 ng/ml]. Children in the vitamin D deficiency group had significantly higher body weight (34.1 +/- 3.8 versus 31.5 +/- 3.3 kg; P < 0.001), body mass index (18.4 +/- 2.2 versus 16.8 +/- 1.7 kg/m(2); P < 0.001), waist circumference (60.1 +/- 8.5 versus 57.2 +/- 7.7 cm; P < 0.001), percentage of body fat (20.2% +/- 2.6% versus 19.1% +/- 2.4%; P < 0.001), and significantly lower concentrations of serum superoxide dismutase (95.38 +/- 12.22 versus 127.62 +/- 15.98 U/mL; P < 0.001) compared with those in the vitamin D sufficiency group. After adjusting for sex, age, body mass index, and percentage of body fat, a positive association between serum 25(OH)D and superoxide dismutase was found (beta = 0.230; P < 0.001). Conclusions: Vitamin D deficiency is common in Harbin schoolchildren. Serum 25(OH)D is closely associated with adiposity and superoxide dismutase in schoolchildren, suggesting that vitamin D deficiency potentially increases the risk for diseases caused by higher adiposity and oxidative stress. |
| 资助信息 | This study was supported by the National Natural Science Foundation of China (No. 81172649 and No.81130049). |
| 语种 | 英语 |
| WOS记录号 | WOS:000340736100013 |
| 公开日期 | 2014-10-10 |
| 源URL | [http://159.226.149.42:8088/handle/152453/8021]  |
| 专题 | 昆明动物研究所_分子人类学 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China 2.Institute for Tuberculosis Control and Prevention of Harbin, Harbin, China 3.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming 650223, China |
| 推荐引用方式 GB/T 7714 | Zhang HQ,Teng JH,Li Y,et al. Vitamin D status and its association with adiposity and oxidative stress in schoolchildren[J]. NUTRITION,2014,30(9):1040-1044. |
| APA | Zhang HQ.,Teng JH.,Li Y.,Li XX.,He YH.,...&Sun CH[*].(2014).Vitamin D status and its association with adiposity and oxidative stress in schoolchildren.NUTRITION,30(9),1040-1044. |
| MLA | Zhang HQ,et al."Vitamin D status and its association with adiposity and oxidative stress in schoolchildren".NUTRITION 30.9(2014):1040-1044. |
入库方式： OAI收割
来源：昆明动物研究所
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