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GENOMICS OF GENE BANKS: A CASE STUDY IN RICE
文献类型：期刊论文
| 作者 | McCouch SR[*]1; McNally KL2; Wang W3; Hamilton RS2 |
| 刊名 | AMERICAN JOURNAL OF BOTANY
 |
| 出版日期 | 2012 |
| 卷号 | 99期号:2页码:407-423 |
| 关键词 | breeding value genetic diversity genotype natural variation next generation sequencing |
| 通讯作者 | srm4@cornell.edu |
| 合作状况 | 其它 |
| 英文摘要 | Only a small fraction of the naturally occurring genetic diversity available in the world's germplasm repositories has been explored to date, but this is expected to change with the advent of affordable, high-throughput genotyping and sequencing technology. It is now possible to examine genome-wide patterns of natural variation and link sequence polymorphisms with downstream phenotypic consequences. In this paper, we discuss how dramatic changes in the cost and efficiency of sequencing and genotyping are revolutionizing the way gene bank scientists approach the responsibilities of their job. Sequencing technology provides a set of tools that can be used to enhance the quality, efficiency, and cost-effectiveness of gene bank operations, the depth of scientific knowledge of gene bank holdings, and the level of public interest in natural variation. As a result, gene banks have the chance to take on new life. Previously seen as "warehouses" where seeds were diligently maintained, but evolutionarily frozen in time, gene banks could transform into vibrant research centers that actively investigate the genetic potential of their holdings. In this paper, we will discuss how genotyping and sequencing can be integrated into the activities of a modern gene bank to revolutionize the way scientists document the genetic identity of their accessions; track seed lots, varieties, and alleles; identify duplicates; and rationalize active collections, and how the availability of genomics data are likely to motivate innovative collaborations with the larger research and breeding communities to engage in systematic and rigorous phenotyping and multilocation evaluation of the genetic resources in gene banks around the world. The objective is to understand and eventually predict how variation at the DNA level helps determine the phenotypic potential of an individual or population. Leadership and vision are needed to coordinate the characterization of collections and to integrate genotypic and phenotypic information in ways that will illuminate the value of these resources. Genotyping of collections represents a powerful starting point that will enable gene banks to become more effective as stewards of crop biodiversity |
| 收录类别 | SCI |
| 资助信息 | We also acknowledge funding support from the U. S. National Science Foundation (Plant Genome Research Program grant #1026555 to S.Mc.) and the U. S. Department of Agriculture (Agriculture and Food Initiative grant #2009- 65300-05698 to S.Mc.), the Generation Challenge Program project G4005.01.07 “ Genotyping of Composite Germplasm Set, Tier 1, Rice ” to K.M. and R.S.H. and a 973 Program (No. 2007CB815700) of China to W.W. |
| 语种 | 英语 |
| WOS记录号 | WOS:000300471100020 |
| 公开日期 | 2012-04-05 |
| 源URL | [http://159.226.149.42:8088/handle/152453/6903]  |
| 专题 | 昆明动物研究所_基因起源组 |
| 作者单位 | 1.Department of Plant Breeding and Genetics, Cornell University, Ithaca, NewYork 14853-1901 USA 2.International Rice Research Institute, DAPO Box 7777, Metro Manila 1301, Philippines 3.Kunming Institute of Zoology, the Chinese Academy of Sciences, No. 32 Jiaochang Donglu Kunming, Yunnan 650223 P.R. China |
| 推荐引用方式 GB/T 7714 | McCouch SR[*],McNally KL,Wang W,et al. GENOMICS OF GENE BANKS: A CASE STUDY IN RICE[J]. AMERICAN JOURNAL OF BOTANY,2012,99(2):407-423. |
| APA | McCouch SR[*],McNally KL,Wang W,&Hamilton RS.(2012).GENOMICS OF GENE BANKS: A CASE STUDY IN RICE.AMERICAN JOURNAL OF BOTANY,99(2),407-423. |
| MLA | McCouch SR[*],et al."GENOMICS OF GENE BANKS: A CASE STUDY IN RICE".AMERICAN JOURNAL OF BOTANY 99.2(2012):407-423. |
入库方式： OAI收割
来源：昆明动物研究所
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