Association of p53 Arg72Pro polymorphism with gastric cancer: a meta-analysis
文献类型：期刊论文
| 作者 | Tang WR1,2; Zhou XH3; Nie SJ4; Yang Z4; Zhu H2; Wu XM2; Zhao RP1; Luo Y[*]1,2 |
| 刊名 | BIOMARKERS
 |
| 出版日期 | 2012 |
| 卷号 | 17期号:7页码:597-603 |
| 关键词 | p53 meta-analysis gastric cancer |
| 通讯作者 | luoyingabc@yahoo.com |
| 合作状况 | 其它 |
| 英文摘要 | Background: p53 tumor suppressor gene Arg72Pro polymorphism has been associated with gastric cancer. However, results were inconsistent. We performed this meta-analysis to estimate the association between p53 Arg72Pro polymorphism and gastric cancer. Methods: An electronic search of PubMed was conducted to select studies. Studies containing available genotype frequencies of Arg72Pro were chosen, and the association was assess by pooled odds ratio (ORs) with 95% confidence interval (CIs). Results: The meta-analysis suggested that the p53 Arg72Pro was associated with the gastric cancer risk (Additive model: OR = 1.149, 95% CI = 1.045-1.263, p = 0.004; Dominant model: OR = 1.18, 95% CI = 1.049-1.328, p = 0.006; Recessive model: OR = 1.202, 95% CI = 1.013-1.427, p = 0.035) in Asian subgroup. Conclusion: This meta-analysis suggests that p53 Arg72Pro polymorphism is associated with increased risk of gastric cancer in Asians. |
| 收录类别 | SCI |
| 资助信息 | This work was financially supported by the National Science Foundation of China (No. 81101547), the Planned Science and Technology Project of Yunnan Province (No. 2009,ZC101M, 2009CA012, 2011DH011), and the Fund of State Key Laboratory of Genetics Resources and Evolution (No. GREKF10-07). |
| 语种 | 英语 |
| WOS记录号 | WOS:000310077200003 |
| 公开日期 | 2013-05-14 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7422]  |
| 专题 | 昆明动物研究所_遗传资源与进化国家重点实验室 昆明动物研究所_基因起源组 |
| 作者单位 | 1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 2.Laboratory of Molecular Genetics of Aging & Tumor, Medical Faculty, Kunming University of Science and Technology, Chenggong Campus, Kunming, China 3.Flower Research Institute of Yunnan Academy of Agricultural Sciences, Kunming, China 4.Kunming Medical University, Kunming, China |
| 推荐引用方式 GB/T 7714 | Tang WR,Zhou XH,Nie SJ,et al. Association of p53 Arg72Pro polymorphism with gastric cancer: a meta-analysis[J]. BIOMARKERS,2012,17(7):597-603. |
| APA | Tang WR.,Zhou XH.,Nie SJ.,Yang Z.,Zhu H.,...&Luo Y[*].(2012).Association of p53 Arg72Pro polymorphism with gastric cancer: a meta-analysis.BIOMARKERS,17(7),597-603. |
| MLA | Tang WR,et al."Association of p53 Arg72Pro polymorphism with gastric cancer: a meta-analysis".BIOMARKERS 17.7(2012):597-603. |
入库方式： OAI收割
来源：昆明动物研究所
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