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The sheep genome illuminates biology of the rumen and lipid metabolism

文献类型:期刊论文

作者Jiang Y1,2,3; Xie M4; Chen WB4; Talbot R5; Maddox JF6; Faraut T7; Wu CH6; Muzny DM8; Li YX4; Zhang WG1,9,10
刊名SCIENCE
出版日期2014
卷号344期号:6188页码:1168-1173
通讯作者brian.dalrymple@csiro.au
英文摘要Sheep (Ovis aries) are a major source of meat, milk, and fiber in the form of wool and represent a distinct class of animals that have a specialized digestive organ, the rumen, that carries out the initial digestion of plant material. We have developed and analyzed a high-quality reference sheep genome and transcriptomes from 40 different tissues. We identified highly expressed genes encoding keratin cross-linking proteins associated with rumen evolution. We also identified genes involved in lipid metabolism that had been amplified and/or had altered tissue expression patterns. This may be in response to changes in the barrier lipids of the skin, an interaction between lipid metabolism and wool synthesis, and an increased role of volatile fatty acids in ruminants compared with nonruminant animals.
收录类别SCI
语种英语
WOS记录号WOS:000336791200050
公开日期2014-06-20
源URL[http://159.226.149.42:8088/handle/152453/7910]  
专题昆明动物研究所_基因起源组
昆明动物研究所_遗传资源与进化国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Zool, State Key Lab Genet Resources & Evolut, Kunming 650223, Peoples R China
2.Commonwealth Sci & Ind Res Org Anim Food & Hlth S, St Lucia, Qld 4067, Australia
3.Northwest A&F Univ, Coll Anim Sci & Technol, Yangling 712100, Peoples R China
4.BGI Shenzhen, Shenzhen 518083, Peoples R China
5.Univ Edinburgh, Ediburgh Genom, Easter Bush EH25 9RG, Midlothian, Scotland
6.Utah State Univ, Logan, UT 84322 USA
7.INRA, Lab Genet Cellulaire, UMR 444, F-31326 Castanet Tolosan, France
8.Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA
9.Inner Mongolia Agr Univ, Hohhot 010018, Peoples R China
10.Nei Mongol Bioinformat, Inst ATCG, Hohhot, Peoples R China
推荐引用方式
GB/T 7714
Jiang Y,Xie M,Chen WB,et al. The sheep genome illuminates biology of the rumen and lipid metabolism[J]. SCIENCE,2014,344(6188):1168-1173.
APA Jiang Y.,Xie M.,Chen WB.,Talbot R.,Maddox JF.,...&Wang W.(2014).The sheep genome illuminates biology of the rumen and lipid metabolism.SCIENCE,344(6188),1168-1173.
MLA Jiang Y,et al."The sheep genome illuminates biology of the rumen and lipid metabolism".SCIENCE 344.6188(2014):1168-1173.

入库方式: OAI收割

来源:昆明动物研究所

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