Reference genome of wild goat (capra aegagrus) and sequencing of goat breeds provide insight into genic basis of goat domestication
文献类型：期刊论文
| 作者 | Dong Y1,2; Zhang XL2; Xie M3; Arefnezhad B4; Wang ZJ3,5; Wang WL3; Feng SH3; Huang GD3; Guan R3; Shen WJ2 |
| 刊名 | BMC GENOMICS
 |
| 出版日期 | 2015 |
| 卷号 | 16期号:X页码:e431 |
| 关键词 | Wild goat genome Animal domestication Artificial selection Coat color evolution Behavioral evolution |
| 通讯作者 | James.Kijas@csiro.au ; h_salekdeh@abrii.ac.ir ; wwang@mail.kiz.ac.cn ; jiangyu96@163.com |
| 合作状况 | 其它 |
| 英文摘要 | Background: Domestic goats (Capra hircus) have been selected to play an essential role in agricultural production systems, since being domesticated from their wild progenitor, bezoar (Capra aegagrus). A detailed understanding of the genetic consequences imparted by the domestication process remains a key goal of evolutionary genomics. Results: We constructed the reference genome of bezoar and sequenced representative breeds of domestic goats to search for genomic changes that likely have accompanied goat domestication and breed formation. Thirteen copy number variation genes associated with coat color were identified in domestic goats, among which ASIP gene duplication contributes to the generation of light coat-color phenotype in domestic goats. Analysis of rapidly evolving genes identified genic changes underlying behavior-related traits, immune response and production-related traits. Conclusion: Based on the comparison studies of copy number variation genes and rapidly evolving genes between wild and domestic goat, our findings and methodology shed light on the genetic mechanism of animal domestication and will facilitate future goat breeding. |
| 收录类别 | SCI |
| 资助信息 | This work was supported by the Chinese 973 program (2013CB835200), the National High Technology Research and Development Program of China (2013AA102506), the Department of Sciences and Technology of Yunnan Province (2013GA004), the National Gene Bank Project of China, State Key Laboratory of Agricultural Genomics, BGI-Shenzhen, Shenzhen, China (2011DQ782025), the Shenzhen Municipal Government of China support funding of State Key Laboratory of Agricultural Genomics (ZDSY20120618171817275) and the special talent recruitment fund of Northwest A&F University. We are grateful to Environmental Protection Administration of Fars Province, Hossein Ali Ebrahimi, Hamzeh Valavi and Saeed Shahini for their assistance in the wild goat sampling. |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/9173]  |
| 专题 | 昆明动物研究所_基因起源组 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Kunming University of Science and Technology, Kunming 650093, China 2.CAS-Max Planck Junior Research Group, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences (CAS), Kunming, Yunnan 650223, China 3.BGI-Shenzhen, Shenzhen 518083, China. 4.Agricultural Biotechnology Research Institute of Iran, Karaj, Iran 5.School of Bioscience and Bioengineering, South China University of Technology, Guangzhou 510006, China 6.CSIRO, Agriculture Flagship, Brisbane 4065QLD, Australia 7.Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark 8.Centre for Social Evolution, Department of Biology, University of Copenhagen, Copenhagen, Denmark 9.Department of Molecular Systems Biology at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran 10.College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China |
| 推荐引用方式 GB/T 7714 | Dong Y,Zhang XL,Xie M,et al. Reference genome of wild goat (capra aegagrus) and sequencing of goat breeds provide insight into genic basis of goat domestication[J]. BMC GENOMICS,2015,16(X):e431. |
| APA | Dong Y.,Zhang XL.,Xie M.,Arefnezhad B.,Wang ZJ.,...&Jiang Y[*].(2015).Reference genome of wild goat (capra aegagrus) and sequencing of goat breeds provide insight into genic basis of goat domestication.BMC GENOMICS,16(X),e431. |
| MLA | Dong Y,et al."Reference genome of wild goat (capra aegagrus) and sequencing of goat breeds provide insight into genic basis of goat domestication".BMC GENOMICS 16.X(2015):e431. |
入库方式： OAI收割
来源：昆明动物研究所
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