Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features
文献类型：期刊论文
| 作者 | Seki R1,2; Li C3,4,5; Hu J2; Xu LH3; Pan HL[1]3; Irie N[*]11; Tamura K[*]2; Zhang GJ[*]3,4,12; Fang Q3,4; Hayashi S2,6 |
| 刊名 | NATURE COMMUNICATIONS
 |
| 出版日期 | 2017 |
| 卷号 | 8期号:X页码:e14229 |
| 通讯作者 | irie@bs.s.u-tokyo.ac.jp ; tam@m.tohoku.ac.jp ; zhanggj@genomics.cn |
| 英文摘要 | Unlike microevolutionary processes, little is known about the genetic basis of macroevolutionary processes. One of these magnificent examples is the transition from non-avian dinosaurs to birds that has created numerous evolutionary innovations such as self-powered flight and its associated wings with flight feathers. By analysing 48 bird genomes, we identified millions of avian-specific highly conserved elements (ASHCEs) that predominantly (>99%) reside in non-coding regions. Many ASHCEs show differential histone modifications that may participate in regulation of limb development. Comparative embryonic gene expression analyses across tetrapod species suggest ASHCE-associated genes have unique roles in developing avian limbs. In particular, we demonstrate how the ASHCE driven avian-specific expression of gene Sim1 driven by ASHCE may be associated with the evolution and development of flight feathers. Together, these findings demonstrate regulatory roles of ASHCEs in the creation of avian-specific traits, and further highlight the importance of cis-regulatory rewiring during macroevolutionary changes. |
| 收录类别 | SCI |
| 资助信息 | This project was supported by Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13000000) and Lundbeckfonden grant R190-2014-2827. K.T. was supported by JSPS KAKENHI Grant (JP15H04374), grant from The Naito Foundation, and Next Generation World-Leading Researchers from the Cabinet Office, Government of Japan (LS007). R.S., S.E. and H.M. are JSPS Research Fellows (JSPS KAKENHI Grant Numbers JP14J07050 (R.S.), JP15J06859 (S.E.), JP15J06385 (H.M.)). C.L. was partially supported by Lundbeckfonden grant R52-5062 to M.T.P.G.). N.I. was partially supported by Platform Project for Supporting in Drug Discovery and Life Science Research Platform for Dynamic Approaches to Living System from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) and Japan Agency for Medical Research and Development (AMED). Photographs of the adult Cochin bantam and Brahmas bantam and their fertilized eggs were provided by the National BioResource Project (NBRP) Chicken/Quail of the MEXT, Japan. |
| 语种 | 英语 |
| 源URL | [http://159.226.149.26:8080/handle/152453/10825]  |
| 专题 | 昆明动物研究所_基因起源组 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Mammalian Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan 2.Department of Developmental Biology and Neurosciences, Graduate School of Life Sciences, Tohoku University, Aobayama 6-3, Aoba-ku, Sendai 980-8578, Japan 3.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 4.Centre for Social Evolution, Department of Biology, Universitetsparken 15, University of Copenhagen, Copenhagen 2100, Denmark 5.China National GeneBank, BGI-Shenzhen, Shenzhen 518083, China 6.Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen 1350, Denmark. 7.Department of Genetics, Cell Biology and Development, University of Minnesota, 321 Church Street SE, Minneapolis, Minnesota 55455, USA 8.Frontier Research Institute for Interdisciplinary Sciences (FRIS), Tohoku University, Aobayama 6-3, Aoba-ku, Sendai 980-8578, Japan. 9.Norwegian University of Science and Technology, University Museum, N-7491 Trondheim, Norway 10.Department of Integrative Biology University of California, Berkeley, California 94720, USA. |
| 推荐引用方式 GB/T 7714 | Seki R,Li C,Hu J,et al. Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features[J]. NATURE COMMUNICATIONS,2017,8(X):e14229. |
| APA | Seki R.,Li C.,Hu J.,Xu LH.,Pan HL[1].,...&Egawa S.(2017).Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features.NATURE COMMUNICATIONS,8(X),e14229. |
| MLA | Seki R,et al."Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features".NATURE COMMUNICATIONS 8.X(2017):e14229. |
入库方式： OAI收割
来源：昆明动物研究所
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