Analysis of the energies of the triple base triplets
文献类型：期刊论文
| 作者 | Liu SQ1; Yang J1; Bai CL2; Liu CQ[*]1,3 |
| 刊名 | JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
 |
| 出版日期 | 2002 |
| 卷号 | 578期号:X页码:199-207 |
| 关键词 | triplet base triplets ODN strand parallel orientation anti-parallel orientation energy analysis |
| ISSN号 | 0166-1280 |
| 通讯作者 | tbrg@public.km.yn.cn |
| 合作状况 | 其它 |
| 英文摘要 | Sixty-four sets of three-dimensional models of DNA triplex base triplets (TBT) were built up based on codons by homologous modeling method and their energies were minimized. According to sequence of TBT and orientation of the third ODN strand third, the energies of monomers and water-K(+)-TBT ternary complexes of TBT were analyzed. The results showed: (i) The energies of the symmetric parallel monomers are generally lower than those of the symmetric anti-parallel monomers of TBT, but the energies of the symmetric parallel ternary complexes are higher than those of the symmetric anti-parallel ternary complexes of TBT. (ii) No matter TBTs are monomers or ternary complexes, the energies of asymmetric parallel TBTs are generally lower than those of the asymmetric anti-parallel ones. (iii) Although the energies of the parallel TBTs are correlated with those of the anti-parallel ones, the energy differences are significant between them. The results here suggest the sequences of TBTs and the orientations of the third ODN strands are two of the key factors that can influence the formation and stability of TBT. |
| 收录类别 | SCI |
| 原文出处 | 2002578199.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/5249]  |
| 专题 | 昆明动物研究所_其他 昆明动物研究所_细胞与分子进化开放实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Zool, Lab Cellular & Mol Evolut, Kunming 650223, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100081, Peoples R China 3.Yunnan Univ, Modern Biol Ctr, Kunming 650091, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu SQ,Yang J,Bai CL,et al. Analysis of the energies of the triple base triplets[J]. JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM,2002,578(X):199-207. |
| APA | Liu SQ,Yang J,Bai CL,&Liu CQ[*].(2002).Analysis of the energies of the triple base triplets.JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM,578(X),199-207. |
| MLA | Liu SQ,et al."Analysis of the energies of the triple base triplets".JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM 578.X(2002):199-207. |
入库方式： OAI收割
来源：昆明动物研究所
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