Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies
文献类型：期刊论文
| 作者 | Zhang J[*]1,2; Hu J1; Shi XF3; Cao H4; Liu WB4 |
| 刊名 | COMPUTATIONAL BIOLOGY AND CHEMISTRY
 |
| 出版日期 | 2003 |
| 卷号 | 27期号:4-5页码:497-506 |
| 关键词 | gene transcription rate intron regulatory motif oligonucleotide frequency analysis transcriptional regulation yeast |
| ISSN号 | 1476-9271 |
| 通讯作者 | zhangjing@ynu.edu.cn |
| 合作状况 | 其它 |
| 英文摘要 | We conducted a comparative statistical analysis of tetra- through hexanucleotide frequencies in two sets of introns of yeast genes. The first set consisted of introns of genes that have transcription rates higher than 30 mRNAs/h while the second set contained introns of genes whose transcription rates were lower than or equal to 10 mRNAs/h. Some oligonucleotides whose occurrence frequencies in the first set of introns are significantly higher than those in the second set of introns were detected. The frequencies of occurrence of most of these detected oligonucleotides are also significantly higher than those in the exons flanking the introns of the first set. Interestingly some of these detected oligonucleotides are the same as well known "signature" sequences of transcriptional regulatory elements. This could imply the existence of potential positive regulatory motifs of transcription in yeast introns. |
| 收录类别 | SCI |
| 资助信息 | This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx). |
| 原文出处 | 200327497.pdf |
| 语种 | 英语 |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/5293]  |
| 专题 | 昆明动物研究所_其他 昆明动物研究所_细胞与分子进化重点实验室 |
| 作者单位 | 1.The Center of Applied Statistics, Yunnan University, Kunming 650091, China 2.Department of Computer Science, Yunnan University of Finance and Economics, Kunming 650221, China 3.Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming 650223, China 4.The Center of Modern Biology, Yunnan University, Kunming 650091, China |
| 推荐引用方式 GB/T 7714 | Zhang J[*],Hu J,Shi XF,et al. Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies[J]. COMPUTATIONAL BIOLOGY AND CHEMISTRY,2003,27(4-5):497-506. |
| APA | Zhang J[*],Hu J,Shi XF,Cao H,&Liu WB.(2003).Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies.COMPUTATIONAL BIOLOGY AND CHEMISTRY,27(4-5),497-506. |
| MLA | Zhang J[*],et al."Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies".COMPUTATIONAL BIOLOGY AND CHEMISTRY 27.4-5(2003):497-506. |
入库方式： OAI收割
来源：昆明动物研究所
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