Cardioviral RNA structure logo analysis: entropy, correlations, and prediction
文献类型：期刊论文
| 作者 | Chen XZ1,2; Cao H1; Zhang W3; Liu CQ[*]1,4,5 |
| 刊名 | JOURNAL OF BIOLOGICAL PHYSICS
 |
| 出版日期 | 2010 |
| 卷号 | 36期号:2页码:145-159 |
| 关键词 | RNA structure logo Entropy Correlations Predictive motif |
| ISSN号 | 0092-0606 |
| 通讯作者 | ch_xiaozhou@yahoo.com.cn ; liucq@ynu.edu.cn |
| 合作状况 | 其它 |
| 英文摘要 | In recent years, there has been an increased number of sequenced RNAs leading to the development of new RNA databases. Thus, predicting RNA structure from multiple alignments is an important issue to understand its function. Since RNA secondary structures are often conserved in evolution, developing methods to identify covariate sites in an alignment can be essential for discovering structural elements. Structure Logo is a technique established on the basis of entropy and mutual information measured to analyze RNA sequences from an alignment. We proposed an efficient Structure Logo approach to analyze conservations and correlations in a set of Cardioviral RNA sequences. The entropy and mutual information content were measured to examine the conservations and correlations, respectively. The conserved secondary structure motifs were predicted on the basis of the conservation and correlation analyses. Our predictive motifs were similar to the ones observed in the viral RNA structure database, and the correlations between bases also corresponded to the secondary structure in the database. |
| 学科主题 | Biophysics |
| 收录类别 | SCI |
| 原文出处 | 201036145.pdf |
| 公开日期 | 2010-08-24 |
| 源URL | [http://159.226.149.42:8088/handle/152453/5397]  |
| 专题 | 昆明动物研究所_其他 |
| 作者单位 | 1.Modern Biology Research Center, Yunnan University, Kunming 650091, China 2.School of Mathematics and Computer Science, Yunnan Nationalities University, Kunming 650031, China 3.Department of Cell Biology and Genetics, Kunming Medical College, Kunming 650031, China 4.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China 5.Theotetical Biology Research Center, Peking University, Beijing 100871, China |
| 推荐引用方式 GB/T 7714 | Chen XZ,Cao H,Zhang W,et al. Cardioviral RNA structure logo analysis: entropy, correlations, and prediction[J]. JOURNAL OF BIOLOGICAL PHYSICS,2010,36(2):145-159. |
| APA | Chen XZ,Cao H,Zhang W,&Liu CQ[*].(2010).Cardioviral RNA structure logo analysis: entropy, correlations, and prediction.JOURNAL OF BIOLOGICAL PHYSICS,36(2),145-159. |
| MLA | Chen XZ,et al."Cardioviral RNA structure logo analysis: entropy, correlations, and prediction".JOURNAL OF BIOLOGICAL PHYSICS 36.2(2010):145-159. |
入库方式： OAI收割
来源：昆明动物研究所
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