Murine MyaK, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system
文献类型:期刊论文
作者 | Shang EY2,3,4,6; Wang XY2,4; Huang JH2,4; Yoshida W7; Kuroiwa A7; Wolgemuth DJ[*]1,2,3,4,5 |
刊名 | MOLECULAR REPRODUCTION AND DEVELOPMENT
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出版日期 | 2000 |
卷号 | 55期号:4页码:372-378 |
关键词 | protein kinase transcription complexes hormone modulation in situ hybridization mouse embryos |
ISSN号 | 1040-452X |
通讯作者 | djw3@columbia.edu |
合作状况 | 其它 |
英文摘要 | We have cloned a mouse homologue (designated Myak) of the yeast protein kinase YAK1. The 1210 aa open reading frame contains a putative protein kinase domain, nuclear localization sequences and PEST sequences. Myak appears to be a member of a growing family of YAK1-related genes that include Drosophila and human Minibrain as well as a recently identified rat gene ANPK that encode a steroid hormone receptor interacting protein. RNA blot analysis revealed that Myak is expressed at low levels ubiquitously but at high levels in reproductive tissues, including testis, epididymis, ovary, uterus, and mammary gland, as well as in brain and kidney. In situ hybridization analysis on selected tissues revealed that Myak is particularly abundant in the hormonally modulated epithelia of the epididymis, mammary gland, and uterus, in round spermatids in the testis, and in the corpora lutea in the ovary, Myak is also highly expressed in the aqueduct of the adult brain and in the brain and spinal cord of day 12.5 embryos, Mol. Reprod. |
收录类别 | SCI |
资助信息 | National Institutes of Health; Grant number: RO1 HD18122; Grant sponsor: The ChineseAcademy of Sciences. |
原文出处 | 200055372.pdf |
语种 | 英语 |
公开日期 | 2010-08-24 |
源URL | [http://159.226.149.42:8088/handle/152453/5187] ![]() |
专题 | 昆明动物研究所_生殖与发育生物学 |
作者单位 | 1.Department of Genetics and Development, Columbia University College of Physicians and Surgeons, New York, New Yor 2.The Center for Reproductive Sciences, Columbia University College of Physicians and Surgeons, New York, New York 3.The Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, New York 4.Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York 5.The Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, New York 6.The Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan, China 7.Divison of Biological Science, Nagoya University, Japan |
推荐引用方式 GB/T 7714 | Shang EY,Wang XY,Huang JH,et al. Murine MyaK, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system[J]. MOLECULAR REPRODUCTION AND DEVELOPMENT,2000,55(4):372-378. |
APA | Shang EY,Wang XY,Huang JH,Yoshida W,Kuroiwa A,&Wolgemuth DJ[*].(2000).Murine MyaK, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system.MOLECULAR REPRODUCTION AND DEVELOPMENT,55(4),372-378. |
MLA | Shang EY,et al."Murine MyaK, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system".MOLECULAR REPRODUCTION AND DEVELOPMENT 55.4(2000):372-378. |
入库方式: OAI收割
来源:昆明动物研究所
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