Development of Genome-Wide Scan for Selection Signature in Farm Animals
文献类型：期刊论文
| 作者 | Zhang WG1,2,3 |
| 刊名 | JOURNAL OF INTEGRATIVE AGRICULTURE
 |
| 出版日期 | 2013 |
| 卷号 | 12期号:8页码:1461-1470 |
| 关键词 | selection signature population genomics genome-wide animal breeding |
| 通讯作者 | atcgnmbi@aliyun.com |
| 合作状况 | 其它 |
| 英文摘要 | Identifying targets of positive selection in farm animals has, until recently, been frustratingly slow, relying on the analysis of individual candidate genes. Genomics, however, has provided the necessary resources to systematically interrogate the entire genome for signatures of selection. This review described important recent results derived from the application of genome-wide scan to the study of genetic changes in farm animals. These included findings of regions of the genome that showed breed differentiation, evidence of selective sweeps within individual genomes and signatures of demographic events. Particular attention is focused on the study of the implications for domestication. To date, sixteen genome-wide scans for recent or ongoing positive selection have been performed in farm animals. A key challenge is to begin synthesizing these newly constructed maps of selection into a coherent narrative of animal breed evolutionary history and derive a deeper mechanistic understanding of how animal populations improve or evolve. The major insights from the surveyed studies are highlighted and directions for future study are suggested. |
| 收录类别 | SCI |
| 资助信息 | Support for this work was provided by the Inner Mongolia Autonomous Region (2010ZD11), the National Natural Science Foundation of China (30960246, 31260538) and the Key Projects in the National Science & Technology Pillar Program (30960242011BAD28B05). |
| 语种 | 英语 |
| WOS记录号 | WOS:000324348800019 |
| 公开日期 | 2013-10-08 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7691]  |
| 专题 | 昆明动物研究所_其他 |
| 作者单位 | 1.College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, P.R.China 2.Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, P.R.China 3.Institute of ATCG, Nei Mongol Bio-Information, Hohhot 010020, P.R.China |
| 推荐引用方式 GB/T 7714 | Zhang WG. Development of Genome-Wide Scan for Selection Signature in Farm Animals[J]. JOURNAL OF INTEGRATIVE AGRICULTURE,2013,12(8):1461-1470. |
| APA | Zhang WG.(2013).Development of Genome-Wide Scan for Selection Signature in Farm Animals.JOURNAL OF INTEGRATIVE AGRICULTURE,12(8),1461-1470. |
| MLA | Zhang WG."Development of Genome-Wide Scan for Selection Signature in Farm Animals".JOURNAL OF INTEGRATIVE AGRICULTURE 12.8(2013):1461-1470. |
入库方式： OAI收割
来源：昆明动物研究所
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