Genetic affinities of central China populations
文献类型：期刊论文
| 作者 | Zhou HY1; Wang HW2; Tan SN1; Chen Y1; Wang WL3; Tao HX4; Yin ZC1; Zou YH1; Ouyang SM1; Ni B[1]*1 |
| 刊名 | GENETICS AND MOLECULAR RESEARCH
 |
| 出版日期 | 2014 |
| 卷号 | 13期号:1页码:616-625 |
| 关键词 | mtDNA Origin Ethnic group Hunan |
| 通讯作者 | zhouhaiyan111@yahoo.com.cn |
| 合作状况 | 其它 |
| 英文摘要 | Hunan locates in the south-central part of China, to the south of the middle reaches of the Yangtze River and south of Lake Dongting. According to the historical records, the peopling of Hunan by modern human ancestors can ascend to 40 thousand years ago. Thus, to trace the ancient maternal components can offer further insight into the origin of south-central China. In this study, we investigated the mitochondrial DNA of 114 individuals from Hunan Province (including 34 Han, 40 Tujia and 40 Miao). Hypervariable regions I and II of the mtDNA control region were sequenced, and the relative diagnostic variations in coding region according to the updated worldwide phylogeny tree were selected and typed by restriction fragment length polymorphism analysis or direct sequencing. All individuals were classified into specific (sub)haplogroups. By comparison with the surrounding populations, southern China-prevalent haplogroups were detected with relative higher frequency in the Tujia and Miao ethnic populations, such as haplogroup B, with more than 20%, lacking in the Han population, which illustrated its southern origin characters. In addition, we also detected northern of East Asia prevalent haplogroups with a relative higher frequency in Tujia populations than in the Miao and Yao ethnic groups, implying a gene flow from Han populations. However, the language-clustering tendency was supported by our principal component analysis and further genetic estimation results. Han and ethnic groups in central China exhibited specific ancestors related to their closer language affinity, although there was extensively genetic admixture between Han and ethnic groups. |
| 收录类别 | SCI |
| 资助信息 | We are grateful to all the voluntary donors of DNA samples used in this study. We thank the anonymous reviewers for their helpful comments on the manuscript. Research supported by the Foundation of China Hunan Provincial Science and Technology Depart- ment (#2011TF1011, #2012SK3275), the Natural Science Foundation of Yunnan Province (#2011FB106), and the West Light Foundation of The Chinese Academy of Sciences. |
| 语种 | 英语 |
| WOS记录号 | WOS:000331846400065 |
| 公开日期 | 2014-03-28 |
| 源URL | [http://159.226.149.42:8088/handle/152453/7830]  |
| 专题 | 昆明动物研究所_遗传资源与进化国家重点实验室 |
| 作者单位 | 1.Key Laboratory of Genetics and Birth Health of Hunan Province, Family Planning Institute of Hunan Province, Changsha, China 2.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan Province, China 3.Department of PLA 65553 Medical Team, Haicheng, Liaoning, China 4.Department of Medical Laboratory, The 210 Hospital of PLA, Dalian, China |
| 推荐引用方式 GB/T 7714 | Zhou HY,Wang HW,Tan SN,et al. Genetic affinities of central China populations[J]. GENETICS AND MOLECULAR RESEARCH,2014,13(1):616-625. |
| APA | Zhou HY.,Wang HW.,Tan SN.,Chen Y.,Wang WL.,...&Ni B[1]*.(2014).Genetic affinities of central China populations.GENETICS AND MOLECULAR RESEARCH,13(1),616-625. |
| MLA | Zhou HY,et al."Genetic affinities of central China populations".GENETICS AND MOLECULAR RESEARCH 13.1(2014):616-625. |
入库方式： OAI收割
来源：昆明动物研究所
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